Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 8/20 | 0.75 |
| ▸ | CHRM5 known ✓ | P08912 | 6/20 | 0.71 |
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.71 |
| ▸ | CHRM3 known ✓ | P20309 | 5/20 | 0.71 |
| ▸ | CHRM4 known ✓ | P08173 | 4/20 | 0.71 |
| ▸ | BLM | P54132 | 4/20 | 0.77 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xenytropium SCHEMBL24707 | 0.94 | BLM (0.71) | BLMCHRM2PABPC1CYP2C19CHRM5 | |
| Xenytropium SCHEMBL29371652 | 0.94 | BLM (0.71) | BLMCHRM2PABPC1CYP2C19CHRM5 | |
| Xenytropium SCHEMBL29361010 | 0.93 | CHRM2 (0.71) | BLMCHRM2PABPC1CYP2C19CHRM5 | |
| Xenytropium SCHEMBL30428452 | 0.93 | CHRM2 (0.71) | BLMCHRM2PABPC1CYP2C19CHRM5 | |
| Butropium SCHEMBL1650524 | 0.88 | BLM (0.64) | BLMCHRM2PABPC1CYP2C19CHRM5 | |
| Butropium SCHEMBL30185784 | 0.88 | BLM (0.64) | BLMCHRM2PABPC1CYP2C19CHRM5 | |
| Butropium SCHEMBL26023 | 0.88 | BLM (0.64) | BLMCHRM2PABPC1CYP2C19CHRM5 | |
| Butropium SCHEMBL11561521 | 0.88 | BLM (0.64) | BLMCHRM2PABPC1CYP2C19CHRM5 | |
| SCHEMBL14507225 | 0.87 | CHRM2 (0.80) | BLMCHRM2PABPC1CYP2C19CHRM5 | |
| Butropium SCHEMBL29388793 | 0.87 | CHRM2 (0.63) | BLMCHRM2PABPC1CYP2C19CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116626208-B | Liquid chromatography-mass spectrometry combined detection method for galactooligosaccharide and application thereof | 东莞理工学院 | 2023-10-27 | — | — | CN | claimed |
| CN-116626208-A | Liquid chromatography-mass spectrometry combined detection method for galactooligosaccharide and application thereof | 东莞理工学院 | 2023-08-22 | — | — | CN | claimed |
| CN-116313212-A | X-ray film type zone plate and preparation method thereof | 中国科学院微电子研究所 | 2023-06-23 | — | — | CN | claimed |
| US-12511073-B2 | Coarse and fine programming of non-volatile memory cells | SILICON STORAGE TECHNOLOGY, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-20250305102-A1 | STEEL SHEET | NIPPON STEEL CORPORATION (JP) | 2025-10-02 | — | — | US | disclosed |
| EP-3603648-B1 | COMPLEX OF NUCLEIC ACID MEDICINE AND MULTIBRANCHED LIPID | SHIONOGI & CO (JP) | 2025-09-17 | — | — | EP | disclosed |
| US-20250231705-A1 | COARSE AND FINE PROGRAMMING OF NON-VOLATILE MEMORY CELLS | SILICON STORAGE TECHNOLOGY, INC. | 2025-07-17 | — | — | US | disclosed |
| CN-116014079-B | Lignin water-based composite battery binder and preparation method and application of silicon-based negative plate thereof | 广东工业大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-119104751-A | Preparation method of interface APT sample of martensitic stainless steel specific crystal orientation relation | 阳江合金材料实验室 | 2024-12-10 | — | — | CN | disclosed |
| CN-116626208-B | Liquid chromatography-mass spectrometry combined detection method for galactooligosaccharide and application thereof | 东莞理工学院 | 2023-10-27 | — | — | CN | disclosed |
| CN-116806239-A | Liquid crystal resin composition for fan impeller and fan impeller using same | 宝理塑料株式会社 | 2023-09-26 | — | — | CN | disclosed |
| CN-116626208-A | Liquid chromatography-mass spectrometry combined detection method for galactooligosaccharide and application thereof | 东莞理工学院 | 2023-08-22 | — | — | CN | disclosed |
| WO-2023139752-A1 | STEEL SHEET | 日本製鉄株式会社 | 2023-07-27 | — | — | WO | disclosed |
| CN-116313212-A | X-ray film type zone plate and preparation method thereof | 中国科学院微电子研究所 | 2023-06-23 | — | — | CN | disclosed |
| US-11638717-B2 | Complex of nucleic acid medicine and multibranched lipid | SHIONOGI & CO., LTD. (JP) | 2023-05-02 | — | — | US | disclosed |
| CN-116014079-A | Lignin water-based composite battery binder and preparation method and application of silicon-based negative plate thereof | 广东工业大学 | 2023-04-25 | — | — | CN | disclosed |
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | NEURALEXO, INC. | 2022-12-15 | — | — | US | disclosed |
| WO-2022168706-A1 | FAN IMPELLER LIQUID CRYSTAL RESIN COMPOSITION AND FAN IMPELLER WHICH USES SAME | ポリプラスチックス株式会社 | 2022-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11638717-B2 | Complex of nucleic acid medicine and multibranched lipid | FABP1, POLRMT, SREBF1 | CHRM2 4884/4885CHRM5 4878/4885CHRM1 4885/4885 |
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | IRF3, IRF2BP2, STAT1 | CHRM2 4225/4885CHRM5 3395/4885CHRM1 4266/4885 |
| US-12511073-B2 | Coarse and fine programming of non-volatile memory cells | CD69, L1CAM, CACNA1C | CHRM2 40/4885CHRM5 9/4885CHRM1 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.