SCHEMBL29842938

SCHEMBL29842938

C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CS)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CALCR P30988 4/20 0.58
▸ C5AR1 P21730 2/20 0.56
▸ OPRM1 P35372 4/20 0.55
▸ OPRD1 P41143 4/20 0.55
▸ F2 P00734 4/20 0.54
▸ APLNR P35414 1/20 0.53
▸ HCRTR1 O43613 1/20 0.52
▸ HCRTR2 O43614 1/20 0.52
▸ MC4R P32245 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29843080 0.96 CALCR (0.60) CALCRC5AR1OPRM1OPRD1F2
SCHEMBL30233449 0.96 CALCR (0.58) CALCRC5AR1OPRM1OPRD1F2
SCHEMBL30233337 0.92 CALCR (0.60) CALCRC5AR1OPRM1OPRD1F2
SCHEMBL30233460 0.92 CALCR (0.59) CALCRC5AR1OPRM1OPRD1F2
SCHEMBL30233411 0.90 CALCR (0.63) CALCRC5AR1OPRM1OPRD1F2
SCHEMBL30233748 0.89 C5AR1 (0.59) CALCRC5AR1APLNRMC4R
SCHEMBL30233222 0.89 CALCR (0.62) CALCRC5AR1OPRM1OPRD1F2
SCHEMBL30753755 0.89 CALCR (0.62) CALCRC5AR1OPRM1OPRD1F2
SCHEMBL30233814 0.88 C5AR1 (0.63) CALCRC5AR1F2HCRTR1HCRTR2
SCHEMBL30788341 0.88 CALCR (0.58) CALCRC5AR1OPRM1OPRD1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561963-A Nicotine acetylcholine receptor peptide antagonist conotoxin compositions and related methods 格罗制药公司 2024-08-30 — — CN disclosed
CN-117979942-A Multimeric lipid vesicles for delivery of cosmetic agents 格罗制药公司 2024-05-03 — — CN disclosed
US-20240122823-A1 MULTISOME LIPID VESICLES FOR DELIVERY OF COSMETIC AGENTS GLO PHARMA, INC. 2024-04-18 — — US disclosed
US-20240076314-A1 PEPTIDE COMPOSITIONS AND METHODS FOR INHIBITING NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY GLO PHARMA, INC. 2024-03-07 — — US disclosed
EP-4312952-A1 MULTISOME LIPID VESICLES FOR DELIVERY OF COSMETIC AGENTS GLO Pharma, Inc. (US) 2024-02-07 — — EP disclosed
EP-4314013-A1 MULTISOME LIPID VESICLES FOR DELIVERY OF COSMETIC AGENTS GLO Pharma, Inc. (US) 2024-02-07 — — EP disclosed
CN-115702161-A Peptide compositions and methods for inhibiting nicotinic acetylcholine receptor activity 格罗制药公司 2023-02-14 — — CN disclosed
WO-2022204287-A1 MULTISOME LIPID VESICLES FOR DELIVERY OF COSMETIC AGENTS GLO PHARMA, INC. (US) 2022-09-29 — — WO disclosed
WO-2022204308-A1 MULTISOME LIPID VESICLES FOR DELIVERY OF COSMETIC AGENTS GLO PHARMA, INC. (US) 2022-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240076314-A1 PEPTIDE COMPOSITIONS AND METHODS FOR INHIBITING NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY CHRNB1, CHRNG, CHRNA1 CALCR 128/4885C5AR1 52/4885OPRM1 2825/4885
US-20240122823-A1 MULTISOME LIPID VESICLES FOR DELIVERY OF COSMETIC AGENTS LIPA, PLIN5, LIPE CALCR 4453/4885C5AR1 3983/4885OPRM1 4754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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