SCHEMBL2984309

SCHEMBL2984309

C=CCNC(=O)CCCP(=O)(OCC)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AOX1 Q06278 1/20 0.50
HPGD P15428 5/20 0.45
HTT P42858 2/20 0.45
FAAH O00519 1/20 0.45
SMN1; SMN2 Q16637 5/20 0.44
TSHR P16473 1/20 0.44
MAPT P10636 1/20 0.44
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43
RAB9A P51151 1/20 0.43
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
PKM P14618 1/20 0.39
POLB P06746 1/20 0.37
CNR1 P21554 2/20 0.37
CNR2 P34972 2/20 0.37
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2991056 0.78 SMN1; SMN2 (0.56) HPGDHTTFAAHSMN1; SMN2TSHR
SCHEMBL28053086 0.75 NPSR1 (0.58) AOX1HTTMAPTGAAALDH1A1
SCHEMBL777194 0.73 AOX1 (0.66) AOX1
SCHEMBL11312247 0.72 AOX1 (0.59) AOX1TSHRGAAALDH1A1LMNA
SCHEMBL28026572 0.70 AOX1 (0.62) AOX1HTTMAPTGAAALDH1A1
SCHEMBL28693406 0.70 AOX1 (0.62) AOX1HTTMAPTGAAALDH1A1
SCHEMBL9340193 0.70 AOX1 (0.62) AOX1GAAALDH1A1LMNAPOLB
SCHEMBL2515116 0.70 AOX1 (0.66) AOX1GAAALDH1A1LMNAPOLB
SCHEMBL7619919 0.70 AOX1 (0.57) AOX1SMN1; SMN2TSHRALDH1A1PKM
SCHEMBL18486564 0.70 AOX1 (0.50) AOX1SMN1; SMN2TSHRPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060142515-A1 Carboxylic acid derivatives containing phosphorous groups and organically polymerisable groups FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2006-06-29 US claimed
EP-1537130-A1 CARBOXYLIC ACID DERIVATIVES CONTAINING PHOSPHOROUS GROUPS AND ORGANICALLY POLYMERISABLE GROUPS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2005-06-08 EP claimed
WO-2004026884-A1 CARBOXYLIC ACID DERIVATIVES CONTAINING PHOSPHOROUS GROUPS AND ORGANICALLY POLYMERISABLE GROUPS FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2004-04-01 WO claimed
US-7777080-B2 Carboxylic acid derivatives containing phosphorous groups and organically polymerizable groups FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2010-08-17 US disclosed
US-20060142515-A1 Carboxylic acid derivatives containing phosphorous groups and organically polymerisable groups FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2006-06-29 US disclosed
EP-1537130-A1 CARBOXYLIC ACID DERIVATIVES CONTAINING PHOSPHOROUS GROUPS AND ORGANICALLY POLYMERISABLE GROUPS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2005-06-08 EP disclosed
WO-2004026884-A1 CARBOXYLIC ACID DERIVATIVES CONTAINING PHOSPHOROUS GROUPS AND ORGANICALLY POLYMERISABLE GROUPS FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2004-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142515-A1 Carboxylic acid derivatives containing phosphorous groups and organically polymerisable groups CA6, PGD, PHGDH AOX1 1622/4885HPGD 365/4885HTT 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.