Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 17/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299489 | 0.96 | PAK1 (0.49) | PAK1MKNK1MKNK2PAK4TNIK | |
| SCHEMBL298248 | 0.83 | PAK1 (0.56) | PAK1MKNK1MKNK2PAK4ALK | |
| SCHEMBL297099 | 0.83 | BRAF (0.43) | PAK1PAK4TNIKPKN1 | |
| SCHEMBL297910 | 0.81 | CYP2C19 (0.41) | PAK1PAK4TNIKPKN1 | |
| SCHEMBL298168 | 0.81 | PAK1 (0.49) | PAK1MKNK1MKNK2PAK4ALK | |
| SCHEMBL298555 | 0.80 | CYP2C19 (0.41) | PAK1PAK4TNIKPKN1 | |
| SCHEMBL298746 | 0.80 | CAMKK2 (0.57) | PAK1PAK4TNIKPKN1 | |
| SCHEMBL3704923 | 0.80 | PAK1 (0.56) | PAK1MKNK1MKNK2PAK4ALK | |
| SCHEMBL298126 | 0.79 | BRAF (0.42) | PAK1PAK4TNIKPKN1 | |
| SCHEMBL299063 | 0.79 | PAK1 (0.40) | PAK1PAK4TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427433-A1 | SOLID FORMS OF SULFONAMIDES AND AMINO ACIDS | Plexxikon, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |