Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.49 |
| ▸ | FASN | P49327 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30045128 | 0.87 | KMT2A (0.50) | HSD11B1ALDH1A1LMNAHPGDFASN | |
| SCHEMBL23605559 | 0.87 | HSD11B1 (0.44) | HSD11B1POLBGAAALDH1A1LMNA | |
| SCHEMBL24529987 | 0.87 | POLB (0.53) | HSD11B1POLBGAAALDH1A1LMNA | |
| SCHEMBL29844243 | 0.86 | MGLL (0.45) | HSD11B1LMNAFASNPARP10MGLL | |
| SCHEMBL23577766 | 0.86 | HSD11B1 (0.52) | HSD11B1FASNPARP10MGLL | |
| SCHEMBL29843991 | 0.85 | CA12 (0.57) | HSD11B1ALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL23578400 | 0.84 | HSD11B1 (0.42) | HSD11B1ALDH1A1LMNASMN1; SMN2FASN | |
| SCHEMBL23577518 | 0.83 | LMNA (0.49) | HSD11B1ALDH1A1LMNAPARP10KMT2A | |
| SCHEMBL23577420 | 0.83 | KDM4E (0.50) | HSD11B1ALDH1A1LMNAKMT2A | |
| SCHEMBL29844082 | 0.83 | KDM4E (0.50) | HSD11B1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081509-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | Zydus Lifesciences Limited (IN) | 2022-11-02 | — | — | EP | claimed |
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | claimed |
| EP-4081509-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | Zydus Lifesciences Limited (IN) | 2022-11-02 | — | — | EP | disclosed |
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | disclosed |