Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.34 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560981 | 1.00 | LIPG (0.62) | LIPGTDP1ENPP2LIPEPTPN1 | |
| SCHEMBL466443 | 0.84 | LIPG (0.70) | LIPGENPP2LIPELPLHTR1A | |
| SCHEMBL29670134 | 0.84 | LIPG (0.70) | LIPGENPP2LIPELPLHTR1A | |
| SCHEMBL15745852 | 0.82 | LIPG (0.88) | LIPGENPP2LPL | |
| SCHEMBL29377890 | 0.81 | LIPG (0.55) | LIPGENPP2LIPEORAI1ORAI2 | |
| SCHEMBL8530 | 0.81 | LIPG (0.55) | LIPGENPP2LIPEORAI1ORAI2 | |
| SCHEMBL2555935 | 0.80 | LIPG (0.60) | LIPGENPP2LIPEORAI1ORAI2 | |
| SCHEMBL29948801 | 0.80 | LIPG (0.85) | LIPGLPL | |
| SCHEMBL1128560 | 0.80 | LIPG (0.85) | LIPGLPL | |
| SCHEMBL31722854 | 0.80 | LIPG (0.60) | LIPGENPP2LIPEORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715692-A | Application of oxaborane compound in prevention and treatment of plant diseases | 广西田园生化股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| US-20250340516-A1 | Isoquinolinones as Modulators of POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2025-11-06 | — | — | US | disclosed |
| CN-116715692-A | Application of oxaborane compound in prevention and treatment of plant diseases | 广西田园生化股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-115028631-A | Triazole pyrimidine derivative, and pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-09-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250340516-A1 | Isoquinolinones as Modulators of POLRMT | POLRMT, TFAM, UQCRC1 | LIPG 1951/4885TDP1 512/4885ENPP2 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.