Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24952911 | 1.00 | RAB9A (0.52) | RAB9AMAPTALDH1A1ITKFFAR1 | |
| SCHEMBL28854651 | 0.81 | CDK9 (0.43) | RAB9AALDH1A1ITKFFAR1POLB | |
| SCHEMBL29799786 | 0.81 | CDK9 (0.43) | RAB9AALDH1A1ITKFFAR1POLB | |
| SCHEMBL24846069 | 0.80 | RAB9A (0.67) | RAB9APOLBGLSMEN1KMT2A | |
| SCHEMBL29861014 | 0.76 | RAB9A (0.60) | RAB9AMAPTALDH1A1NR3C2L3MBTL1 | |
| SCHEMBL24931553 | 0.76 | RAB9A (0.60) | RAB9AMAPTALDH1A1NR3C2L3MBTL1 | |
| SCHEMBL21394491 | 0.75 | RAB9A (0.43) | RAB9AMAPTALDH1A1ITKFFAR1 | |
| SCHEMBL28854654 | 0.74 | HCAR2 (0.48) | FFAR1GPR52NR3C2GLSDGAT1 | |
| SCHEMBL29846096 | 0.74 | HCAR2 (0.48) | FFAR1GPR52NR3C2GLSDGAT1 | |
| SCHEMBL24954194 | 0.72 | MAPT (0.62) | RAB9AMAPTALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845709-B | MRGPRX2 antagonists for the treatment of inflammatory disorders | 德米拉公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114845709-A | MRGPRX2 antagonists for use in treating inflammatory disorders | 德米拉公司 | 2022-08-02 | — | — | CN | disclosed |