Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799786 | 1.00 | CDK9 (0.43) | CDK9CTSSCTSKTSHRLMNA | |
| SCHEMBL24952911 | 0.81 | RAB9A (0.52) | FFAR1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL29846147 | 0.81 | RAB9A (0.52) | FFAR1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL24622540 | 0.80 | CYP17A1 (0.44) | LMNASMN1; SMN2POLBITKNPC1 | |
| SCHEMBL26388177 | 0.80 | LMNA (0.52) | TSHRLMNAALDH1A1NPSR1MEN1 | |
| SCHEMBL15235889 | 0.76 | CYP17A1 (0.39) | GLSCYP17A1 | |
| SCHEMBL28183900 | 0.72 | SYK (0.43) | KCNQ4KCNQ5 | |
| SCHEMBL21394491 | 0.72 | RAB9A (0.43) | FFAR1ALDH1A1MEN1KMT2AITK | |
| SCHEMBL14507524 | 0.71 | CA1 (0.41) | CYP17A1 | |
| SCHEMBL29846096 | 0.71 | HCAR2 (0.48) | FFAR1GLSGPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845709-A | MRGPRX2 antagonists for use in treating inflammatory disorders | 德米拉公司 | 2022-08-02 | — | — | CN | disclosed |