Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.59 |
| ▸ | INSR | P06213 | 8/20 | 0.56 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16800095 | 0.98 | ADRB2 (0.61) | ADRB2ADRB1INSRSNCAMAPT | |
| SCHEMBL14561804 | 0.98 | ADRB2 (0.61) | ADRB2ADRB1INSRSNCAMAPT | |
| Iodide SCHEMBL6246881 | 0.82 | INSR (0.70) | ADRB2ADRB1INSRSNCAMAPT | |
| Iodide SCHEMBL5377348 | 0.79 | ADRB2 (0.53) | ADRB2ADRB1INSRSNCAMAPT | |
| Hydrochloric Acid SCHEMBL11516423 | 0.77 | INSR (0.60) | ADRB2ADRB1INSRSNCAMAPT | |
| Hydrochloric Acid SCHEMBL11516421 | 0.77 | INSR (0.60) | ADRB2ADRB1INSRSNCAMAPT | |
| SCHEMBL16800102 | 0.77 | MAPT (0.63) | INSRMAPTPOLBHTTRAB9A | |
| SCHEMBL16520745 | 0.77 | ADRB2 (0.54) | ADRB2ADRB1INSRSNCAMAPT | |
| SCHEMBL7762854 | 0.77 | ADRB2 (0.54) | ADRB2ADRB1INSRSNCAMAPT | |
| SCHEMBL30846518 | 0.77 | ADRB2 (0.54) | ADRB2ADRB1INSRSNCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115032136-A | Hemolytic reagent, kit and method for classifying leukocytes | 希森美康株式会社 | 2022-09-09 | — | — | CN | disclosed |