Gfttgrrgdlatihgmnrpf

Gfttgrrgdlatihgmnrpf

SCHEMBL29847206

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 8/20 0.66
▸ NPY4R P50391 8/20 0.66
▸ NPY5R Q15761 8/20 0.66
▸ NPY1R P25929 8/20 0.66
▸ RAMP3 O60896 6/20 0.63
▸ CALCR P30988 6/20 0.63
▸ MAPK8 P45983 1/20 0.62
▸ MAPK9 P45984 1/20 0.62
▸ MAPK10 P53779 1/20 0.62
▸ TFPI P10646 1/20 0.62
▸ CXCR4 P61073 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30607310 0.88 CALCR (0.66) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30397368 0.87 NPY2R (0.82) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30574247 0.86 NPY2R (0.74) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30436941 0.86 CALCR (0.64) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30262071 0.86 KEAP1 (0.62) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL29977603 0.86 NPY2R (0.69) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL9979655 0.85 NPY2R (0.69) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30495784 0.85 NPY2R (0.70) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31050076 0.84 GLP1R (0.66) NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL29754385 0.84 MAPK8 (0.64) NPY2RNPY4RNPY5RNPY1RRAMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731270-A1 COMBINATION THERAPY WITH PEPTIDE RECEPTOR RADIONUCLIDE AND DNA REPAIR INHIBITOR The Regents of The University of California (US) 2026-04-29 — — EP disclosed
US-12612445-B2 Therapeutic agents KING'S COLLEGE LONDON (GB) 2026-04-28 — — US disclosed
US-12509499-B2 Therapeutic agents KING'S COLLEGE LONDON (GB) 2025-12-30 — — US disclosed
WO-2024263637-A1 COMBINATION THERAPY WITH PEPTIDE RECEPTOR RADIONUCLIDE AND DNA REPAIR INHIBITOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-26 — — WO disclosed
CN-118510814-A Chimeric antigen receptor and application thereof 星尘生物科技(上海)有限公司 2024-08-16 — — CN disclosed
US-20240228576-A1 THERAPEUTIC AGENTS KING'S COLLEGE LONDON (GB) 2024-07-11 — — US disclosed
US-20240101601-A1 BI-TERMINAL PEGYLATED INTEGRIN-BINDING PEPTIDES AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-28 — — US disclosed
US-20240076348-A1 THERAPEUTIC AGENTS KING'S COLLEGE LONDON (GB) 2024-03-07 — — US disclosed
WO-2023217062-A1 CHIMERIC ANTIGEN RECEPTOR AND USE THEREOF 星尘生物科技(上海)有限公司 2023-11-16 — — WO disclosed
US-11802143-B2 Therapeutic agents KING'S COLLEGE LONDON (GB) 2023-10-31 — — US disclosed
US-20230183317-A1 METHODS OF DETECTING AND TREATING LUNG DAMAGE IN RESPIRATORY-RELATED VIRAL INFECTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-06-15 — — US disclosed
EP-4146268-A2 METHODS OF DETECTING AND TREATING LUNG DAMAGE IN RESPIRATORY-RELATED VIRAL INFECTIONS The Regents of the University of California (US) 2023-03-15 — — EP disclosed
US-11485758-B2 Bi-terminal pegylated integrin-binding peptides and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-11-01 — — US disclosed
EP-3131566-B1 BI-TERMINAL PEGYLATED INTEGRIN-BINDING PEPTIDES AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2022-10-05 — — EP disclosed
CN-107735407-B Therapeutic agents 伦敦国王学院 2022-08-16 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509499-B2 Therapeutic agents IL2RA, CD4, TNFRSF9 NPY2R 421/4885NPY4R 659/4885NPY5R 1156/4885
US-12612445-B2 Therapeutic agents CD40, TNFRSF9, HAVCR2 NPY2R 768/4885NPY4R 722/4885NPY5R 1499/4885
US-20230183317-A1 METHODS OF DETECTING AND TREATING LUNG DAMAGE IN RESPIRATORY-RELATED VIRAL INFECTIONS ACE2, ACE, MAVS NPY2R 4258/4885NPY4R 4508/4885NPY5R 4491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback