SCHEMBL29847323

SCHEMBL29847323

CC(=O)c1cccc(N(CC(=O)Nc2ccccc2Sc2ccccc2)S(C)(=O)=O)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPSR1 Q6W5P4 9/20 0.77
▸ LMNA P02545 3/20 0.77
▸ RECQL P46063 1/20 0.77
▸ KMT2A Q03164 4/20 0.68
▸ MEN1 O00255 2/20 0.68
▸ TSHR P16473 2/20 0.64
▸ USP2 O75604 1/20 0.62
▸ MAPT P10636 2/20 0.62
▸ GAA P10253 2/20 0.60
▸ ALDH1A1 P00352 4/20 0.56
▸ CYP3A4 P08684 2/20 0.55
▸ CYP2D6 P10635 2/20 0.55
▸ CYP2C9 P11712 2/20 0.55
▸ CYP2C19 P33261 2/20 0.55
▸ ALOX15 P16050 1/20 0.55
▸ HPGD P15428 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ HTT P42858 1/20 0.54
▸ POLB P06746 3/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24445728 1.00 NPSR1 (0.77) NPSR1LMNARECQLKMT2AMEN1
SCHEMBL30950630 0.93 NPSR1 (0.78) NPSR1LMNARECQLKMT2AMEN1
SCHEMBL30950633 0.90 NPSR1 (0.74) NPSR1LMNARECQLKMT2AMEN1
SCHEMBL30950617 0.88 NPSR1 (0.80) NPSR1LMNARECQLKMT2AMEN1
SCHEMBL30950635 0.85 NPSR1 (0.66) NPSR1LMNARECQLKMT2AMEN1
SCHEMBL30950611 0.85 NPSR1 (0.66) NPSR1LMNARECQLKMT2AMEN1
SCHEMBL30950622 0.85 NPSR1 (0.66) NPSR1LMNARECQLKMT2AMEN1
SCHEMBL30950624 0.85 NPSR1 (0.66) NPSR1LMNARECQLKMT2AMEN1
SCHEMBL30950618 0.84 NPSR1 (0.65) NPSR1LMNARECQLKMT2AMEN1
SCHEMBL30950613 0.84 NPSR1 (0.65) NPSR1LMNARECQLKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4000609-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES UNIV NAT CHONNAM IND FOUND (KR) 2024-11-13 — — EP claimed
US-20220313633-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) 2022-10-06 — — US claimed
EP-4000609-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES UNIV NAT CHONNAM IND FOUND (KR) 2024-11-13 — — EP disclosed
US-20220313633-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) 2022-10-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220313633-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES HPGDS, ARG1, RELA NPSR1 1811/4885LMNA 3444/4885RECQL 3544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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