Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13035673 | 0.87 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL7336644 | 0.85 | ALDH1A1 (0.62) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL20854567 | 0.85 | ALDH1A1 (0.62) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL2341345 | 0.85 | ALDH1A1 (0.62) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL29847574 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL4368155 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL21882038 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL21819606 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL21050147 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL16057959 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385847-B | Polysubstituted diaryl compound, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2023-09-29 | — | — | CN | disclosed |
| CN-115385847-A | Polysubstituted diaryl compound and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-11-25 | — | — | CN | disclosed |
| CN-113387873-B | Substituted diaryl compound, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-09-20 | — | — | CN | disclosed |