Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 3/20 | 0.71 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.59 |
| ▸ | KDR | P35968 | 3/20 | 0.59 |
| ▸ | JAK2 | O60674 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | WEE1 | P30291 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | TTK | P33981 | 2/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 6/20 | 0.48 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16515483 | 1.00 | FGFR2 (0.71) | FGFR2FGFR1KDRJAK2BRD4 | |
| SCHEMBL21155993 | 0.89 | FGFR2 (0.75) | FGFR2FGFR1KDRJAK2BRD4 | |
| SCHEMBL16514362 | 0.88 | JAK2 (0.70) | FGFR2FGFR1KDRJAK2BRD4 | |
| SCHEMBL29846917 | 0.88 | JAK2 (0.70) | FGFR2FGFR1KDRJAK2BRD4 | |
| SCHEMBL19119650 | 0.85 | FGFR2 (0.81) | FGFR2FGFR1KDRJAK2BRD4 | |
| SCHEMBL16514799 | 0.85 | JAK2 (0.66) | FGFR2JAK2BRD4EGFRJUN | |
| SCHEMBL29847922 | 0.84 | JAK2 (0.56) | FGFR2FGFR1JAK2BRD4EGFR | |
| SCHEMBL16514760 | 0.84 | JAK2 (0.56) | FGFR2FGFR1JAK2BRD4EGFR | |
| SCHEMBL16823187 | 0.84 | JAK2 (0.56) | FGFR2FGFR1KDRJAK2BRD4 | |
| SCHEMBL16513666 | 0.83 | FGFR2 (1.00) | FGFR2FGFR1KDRJAK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |