Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | F7 | P08709 | 3/20 | 0.44 |
| ▸ | F3 | P13726 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963742 | 1.00 | PPARG (0.49) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL30537451 | 1.00 | PPARG (0.49) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL30537450 | 1.00 | PPARG (0.49) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL4316052 | 1.00 | PPARG (0.49) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL14538124 | 1.00 | PPARG (0.49) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL31138123 | 1.00 | PPARG (0.49) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL2586056 | 1.00 | PPARG (0.49) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL594566 | 1.00 | PPARG (0.49) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL29896525 | 0.90 | PPARG (0.52) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL14035899 | 0.85 | DNTT (0.48) | PPARGPPARDPPARATRPA1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250311723-A1 | METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS | IMPELLO BIOSCIENCES, INC. | 2025-10-09 | — | — | US | disclosed |
| EP-4188090-A2 | METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS | Impello Biosciences, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |
| US-11638427-B2 | Methods and compositions for altering secondary metabolites in plants | IMPELLO BIOSCIENCES, INC. (US) | 2023-05-02 | — | — | US | disclosed |
| WO-2022026613-A2 | METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS | IMPELLO BIOSCIENCES, INC. (US) | 2022-02-03 | — | — | WO | disclosed |
| US-7786348-B2 | Methods for producing pathogen-resistant plants with allene oxide synthase and divinyl ether synthase, and the amino acid and nucleotide sequences thereof | BASF PLANT SCIENCE GMBH (DE) | 2010-08-31 | — | — | US | disclosed |
| US-20090144856-A1 | Methods for producing pathogen-resistant plants with allene oxide synthase and divinyl ether synthase, and the amino acid and nucleotide sequences thereof | BASF PLANT SCIENCE GMBH (DE) | 2009-06-04 | — | — | US | disclosed |
| US-7393946-B1 | Method of modulating metabolite biosynthesis in recombinant cells | RIJKSUNIVERSITEIT LEIDEN (NL) | 2008-07-01 | — | — | US | disclosed |
| US-7321025-B2 | Isolated oxide synthase and divinyl ether synthase and uses thereof | BASF PLANT SCIENCE GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| CN-1304570-C | Allene oxide synthase and divinyl ether synthase from the C Y P 7 4-enzyme family isolated out of physcomitrella patens, the nucleotide sequences that code these synthases, and method for producing pa | BASF PLANT SCIENCE GMBH (DE) | 2007-03-14 | — | — | CN | disclosed |
| US-20050223437-A1 | Allene oxide synthase and divinyl ether synthase from the cyp74-enzyme family isolated out of physcomitrella patens, the nucleotide sequences that code these synthases, and method for producing pathogen-resistant plants | BASF PLANT SCIENCE GMBH (DE) | 2005-10-06 | — | — | US | disclosed |
| US-20040259906-A1 | Methods for controlling the proliferation of cells | JOHN HOPKINS UNIVERSITY | 2004-12-23 | — | — | US | disclosed |
| WO-2004091516-A2 | METHODS FOR CONTROLLING THE PROLIFERATION OF CELLS | JOHNS HOPKINS UNIVERSITY (US) | 2004-10-28 | — | — | WO | disclosed |
| US-20040137590-A1 | Allene oxide cyclase gene and use thereof for producing jasmonic acid | INSTITUT FUR PFLANZENBIOCHEMIE (DE) | 2004-07-15 | — | — | US | disclosed |
| EP-1252318-A2 | ALLENE OXIDE CYCLASE GENE AND USE THEREOF FOR PRODUCING JASMONIC ACID | Institut für Pflanzenbiochemie (DE) | 2002-10-30 | — | — | EP | disclosed |
| WO-2002068644-A1 | PROMOTER OF S-ADENOSYL-L-METHIONINE: JASMONIC ACID CARBOXYL METHYL TRANSFERASE GENE AND METHOD FOR PRODUCING TARGET PROTEIN IN PLANTS USING THE SAME | SCIGEN HARVEST CO., LTD (KR) | 2002-09-06 | — | — | WO | disclosed |
| EP-1157119-A1 | METHOD OF MODULATING METABOLITE BIOSYNTHESIS IN RECOMBINANT CELLS | RIJKSUNIVERSITEIT LEIDEN (NL) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001057224-A2 | ALLENE OXIDE CYCLASE GENE AND USE THEREOF FOR PRODUCING JASMONIC ACID | INSTITUT FÜR PFLANZENBIOCHEMIE (DE) | 2001-08-09 | — | — | WO | disclosed |
| WO-2000046383-A2 | METHOD OF MODULATING METABOLITE BIOSYNTHESIS IN RECOMBINANT CELLS | RIJKSUNIVERSITEIT LEIDEN (NL) | 2000-08-10 | — | — | WO | disclosed |
| WO-1997046695-A1 | PROCESS FOR PREPARING CYCLIC KETONES | FIRMENICH S.A. (CH) | 1997-12-11 | — | — | WO | disclosed |
| US-5017386-A | Lipoxygenase | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1991-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250311723-A1 | METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS | ERG28, AHCY, BROX | PPARG 3402/4885PPARD 4049/4885PPARA 3441/4885 |
| US-11638427-B2 | Methods and compositions for altering secondary metabolites in plants | ERG28, AHCY, BROX | PPARG 3402/4885PPARD 4049/4885PPARA 3441/4885 |
| US-20040259906-A1 | Methods for controlling the proliferation of cells | MKI67, BCL6, BCL3 | PPARG 1607/4885PPARD 1510/4885PPARA 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.