Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30631605 | 0.80 | P2RY14 (0.50) | P2RY14NOTUMMEN1KMT2ADDB1 | |
| SCHEMBL537933 | 0.76 | ULK1 (0.54) | MEN1KMT2ADDB1CRBNBAZ1A | |
| SCHEMBL29850847 | 0.75 | EPHX2 (0.63) | KMT2ANPC1 | |
| SCHEMBL1459680 | 0.75 | CHRNA7 (0.55) | P2RY14NOTUMMEN1KMT2ABAZ1A | |
| SCHEMBL4855527 | 0.74 | P2RY14 (0.62) | P2RY14NOTUMMEN1KMT2ABAZ1A | |
| SCHEMBL21296709 | 0.74 | P2RY14 (0.62) | P2RY14NOTUMMEN1KMT2ABAZ1A | |
| SCHEMBL22860096 | 0.74 | P2RY14 (0.65) | P2RY14NOTUMMEN1KMT2ABAZ1A | |
| Hydrochloric Acid SCHEMBL4280960 | 0.74 | CHRNA7 (0.56) | P2RY14NOTUMMEN1KMT2ABAZ1A | |
| Hydrochloric Acid SCHEMBL23360201 | 0.72 | DDB1 (0.52) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL23360203 | 0.72 | DDB1 (0.52) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291188-A1 | INHIBITORS OF CGAS ACTIVITY AS THERAPEUTIC AGENTS | Bellbrook Labs, Llc (US) | 2023-12-20 | — | — | EP | claimed |
| WO-2022174012-A1 | INHIBITORS OF cGAS ACTIVITY AS THERAPEUTIC AGENTS | BELLBROOK LABS, LLC (US) | 2022-08-18 | — | — | WO | claimed |