Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197857 | 0.86 | CYP3A4 (0.41) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL19812427 | 0.81 | ALDH1A1 (0.43) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL5322857 | 0.81 | ALDH1A1 (0.43) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11761457 | 0.80 | MEN1 (0.33) | CYP3A4MEN1ALOX15KMT2A | |
| SCHEMBL11547425 | 0.79 | ALDH1A1 (0.42) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL2757911 | 0.79 | CYP3A4 (0.42) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL3274456 | 0.79 | ALDH1A1 (0.42) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL10834300 | 0.79 | LMNA (0.52) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL8306636 | 0.78 | CYP3A4 (0.40) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL1436756 | 0.78 | MEN1 (0.39) | CYP3A4LMNAMEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858790-B2 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-12-28 | — | — | US | claimed |
| US-7786107-B2 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-08-31 | — | — | US | claimed |
| EP-2040706-A2 | MODULATORS OF MUSCARINIC RECEPTORS | Vertex Pharmceuticals Incorporated (US) | 2009-04-01 | — | — | EP | claimed |
| US-20080033002-A1 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED | 2008-02-07 | — | — | US | claimed |
| WO-2008005295-A2 | MODULATORS OF MUSCARINIC RECEPTORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-01-10 | — | — | WO | claimed |
| CN-103229104-A | Composition for forming resist underlayer film containing hydroxyl group-containing carbazole novolac resin | NISSAN CHEMICAL IND LTD | 2013-07-31 | — | — | CN | disclosed |
| US-7858790-B2 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-12-28 | — | — | US | disclosed |
| US-7786107-B2 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-08-31 | — | — | US | disclosed |
| US-20100063021-A9 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS (SAN DIEGO) LLC | 2010-03-11 | — | — | US | disclosed |
| US-7667230-B2 | Electronic devices containing acene-thiophene copolymers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-02-23 | — | — | US | disclosed |
| US-7608679-B2 | for use in semiconductors, electronics such as organic thin film transistors, light emitting diodes, and photovoltaic cells | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-10-27 | — | — | US | disclosed |
| EP-2051715-A2 | MODULATORS OF MUSCARINIC RECEPTORS | Vertex Pharmceuticals Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| US-20070232781-A1 | ACENE-THIOPHENE COPOLYMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2007-10-04 | — | — | US | disclosed |
| US-20070228360-A1 | ELECTRONIC DEVICES CONTAINING ACENE-THIOPHENE COPOLYMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2007-10-04 | — | — | US | disclosed |
| US-4376094-A | Method of disinfecting and a method for destroying bacteria and fungi using 2-substituted glutaraldehydes | STERLING DRUG INC. (US) | 1983-03-08 | — | — | US | disclosed |
| US-4222963-A | Substituted propargyl alcohols, allylic alcohols and unsaturated ketones, and methods for the production thereof | KURARAY CO., LTD. (JP) | 1980-09-16 | — | — | US | disclosed |
| US-4179579-A | PERFUMES | KURARAY CO., LTD. (JP) | 1979-12-18 | — | — | US | disclosed |
| US-4137273-A | INSECTICIDES, CHEMICAL INTERMEDIATES | ZOECON CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |
| US-4122119-A | Process for the production of unsaturated ketones | KURARAY CO., LTD. (JP) | 1978-10-24 | — | — | US | disclosed |
| US-4055634-A | ALUMINUM ALKOXIDE | HOFFMANN-LA ROCHE, INC. (US) | 1977-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063021-A9 | Modulators of muscarinic receptors | CHRM3, CHRM5, CHRM2 | CYP3A4 1260/4885ALDH1A1 2356/4885TDP1 4014/4885 |
| US-20080033002-A1 | Modulators of muscarinic receptors | CHRM3, CHRM5, CHRM2 | CYP3A4 1260/4885ALDH1A1 2356/4885TDP1 4014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.