SCHEMBL8306636

SCHEMBL8306636

COC(C)(C)CCCC(C)C

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.40
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.39
ALOX15 P16050 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.38
BLM P54132 1/20 0.31
CA1 P00915 1/20 0.31
PTPN2 P17706 1/20 0.30
PTPN1 P18031 1/20 0.30
CDC25B P30305 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10834300 0.91 LMNA (0.52) CYP3A4ALDH1A1TDP1LMNAMEN1
SCHEMBL13239742 0.84 ALDH1A1 (0.41) CYP3A4ALDH1A1TDP1LMNATSHR
SCHEMBL11546962 0.83 ALDH1A1 (0.39) CYP3A4ALDH1A1TDP1LMNATSHR
SCHEMBL8858043 0.82 MEN1 (0.41) CYP3A4ALDH1A1LMNAMEN1ALOX15
SCHEMBL11547671 0.81 ALDH1A1 (0.38) CYP3A4ALDH1A1TDP1LMNATSHR
SCHEMBL19812427 0.79 ALDH1A1 (0.43) CYP3A4ALDH1A1TDP1LMNAMEN1
SCHEMBL114177 0.79 ALDH1A1 (0.37) CYP3A4ALDH1A1TDP1LMNATSHR
SCHEMBL5322857 0.79 ALDH1A1 (0.43) CYP3A4ALDH1A1TDP1LMNAMEN1
SCHEMBL3274456 0.78 ALDH1A1 (0.42) CYP3A4ALDH1A1TDP1LMNAMEN1
SCHEMBL2985136 0.78 CYP3A4 (0.42) CYP3A4ALDH1A1TDP1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11725010-B2 Polyheterocyclic compounds as METTL3 inhibitors STORM THERAPEUTICS LIMITED (GB) 2023-08-15 US disclosed
CN-109310602-B Fragrance material 高砂香料工业株式会社 2022-06-28 CN disclosed
CN-107207994-B Photolabile acetal and ketal compounds for controlled release of active volatile carbonyl compounds 弗门尼舍有限公司 2021-06-18 CN disclosed
WO-2004099200-A1 ISOXAZOLE AND ISOTHIAZOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS PFIZER PRODUCTS INC. (US) 2004-11-18 WO disclosed
US-4338469-A PAINT ADDITIVE SUNTECH, INC. (US) 1982-07-06 US disclosed
US-4292219-A Latex-base paint containing 2-methoxy-2-phenyl propane or 8-methoxy-p-menthane SUNTECH, INC. (PA) 1981-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11725010-B2 Polyheterocyclic compounds as METTL3 inhibitors METTL3, DIMT1, TPMT CYP3A4 2615/4885ALDH1A1 2056/4885TDP1 1158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.