Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.36 |
| ▸ | FEN1 | P39748 | 5/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824100 | 1.00 | ALOX5AP (0.36) | ALOX5APFEN1PDK2DGAT1BRD4 | |
| SCHEMBL23294447 | 0.88 | DGAT1 (0.40) | ALOX5APFEN1DGAT1 | |
| SCHEMBL29851912 | 0.88 | DGAT1 (0.40) | ALOX5APFEN1DGAT1 | |
| SCHEMBL29852091 | 0.84 | LPL (0.33) | DGAT1 | |
| SCHEMBL23294380 | 0.84 | LPL (0.33) | DGAT1 | |
| SCHEMBL23328998 | 0.79 | DGAT1 (0.35) | PDK2DGAT1 | |
| SCHEMBL3508463 | 0.72 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL23294549 | 0.69 | LPL (0.41) | DGAT1 | |
| SCHEMBL23326031 | 0.66 | NPC1 (0.34) | DGAT1 | |
| SCHEMBL15741938 | 0.65 | DGAT1 (0.34) | ALOX5APFEN1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |