Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23294380 | 1.00 | LPL (0.33) | LPLLIPGDGAT1IRAK4FFAR1 | |
| SCHEMBL23294549 | 0.84 | LPL (0.41) | LPLLIPGDGAT1IRAK4FFAR1 | |
| SCHEMBL28824100 | 0.84 | ALOX5AP (0.36) | DGAT1 | |
| SCHEMBL29851978 | 0.84 | ALOX5AP (0.36) | DGAT1 | |
| SCHEMBL23294447 | 0.83 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL29851912 | 0.83 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL23294597 | 0.79 | UCHL1 (0.31) | DGAT1 | |
| SCHEMBL29852138 | 0.79 | UCHL1 (0.31) | DGAT1 | |
| SCHEMBL9953694 | 0.74 | ALPL (0.34) | DGAT1 | |
| SCHEMBL23328998 | 0.74 | DGAT1 (0.35) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051667-A1 | HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS | Lilac Therapeutics, Inc. (US) | 2022-09-07 | — | — | EP | disclosed |
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |