SCHEMBL29852003

SCHEMBL29852003

CCOC(=O)c1nn(COCC[Si](C)(C)C)nc1-c1ccc2c(c1)Cc1cc(B3OC(C)(C)C(C)(C)O3)ccc1-2

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
UCHL1 P09936 1/20 0.31
LIPG Q9Y5X9 1/20 0.31
ROCK1 Q13464 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29852125 1.00 UCHL1 (0.31) UCHL1LIPGROCK1
SCHEMBL23294578 1.00 UCHL1 (0.31) UCHL1LIPGROCK1
SCHEMBL29852138 0.88 UCHL1 (0.31) UCHL1
SCHEMBL23294597 0.88 UCHL1 (0.31) UCHL1
SCHEMBL23294581 0.87 UCHL1 (0.36) UCHL1LIPG
SCHEMBL23294656 0.86 LIPG (0.36) UCHL1LIPG
SCHEMBL31499493 0.84 ELANE (0.35)
SCHEMBL23294708 0.84 ELANE (0.35)
SCHEMBL23294586 0.84 GABRG2 (0.40)
SCHEMBL29852202 0.84 ELANE (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4051667-B1 HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS LILAC THERAPEUTICS INC (US) 2026-01-28 EP disclosed
EP-4051667-A1 HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS Lilac Therapeutics, Inc. (US) 2022-09-07 EP disclosed
CN-114929676-A Heterocyclic carboxylate compounds as glycolate oxidase inhibitors 紫丁香疗法有限公司 2022-08-19 CN disclosed