Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | LATS1 | O95835 | 7/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327145 | 0.83 | ALDH1A1 (0.46) | CTSAHDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL12664041 | 0.80 | CTSA (0.43) | CTSAHDAC3HDAC1HDAC2LATS1 | |
| SCHEMBL28187527 | 0.80 | CTSA (0.40) | CTSAHDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL4312684 | 0.80 | MGAM (0.56) | KMT2ACNR2RAB9A | |
| SCHEMBL2445721 | 0.79 | CYP1A2 (0.54) | CTSAHDAC3HDAC1HDAC2RAB9A | |
| SCHEMBL10201993 | 0.77 | CTSA (0.45) | CTSAHDAC3HDAC1HDAC2ACKR3 | |
| SCHEMBL27776426 | 0.77 | KDM4E (0.50) | CTSAHDAC3HDAC1HDAC2CNR1 | |
| SCHEMBL23458543 | 0.76 | HSD17B14 (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4296569 | 0.75 | ROCK2 (0.47) | LATS1LATS2RAB9A | |
| SCHEMBL1016413 | 0.75 | MGAM (0.58) | CTSAHDAC3HDAC1HDAC2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929697-A | Azabenzimidazole compounds and medicaments | 日本新药株式会社 | 2022-08-19 | — | — | CN | disclosed |