Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15020039 | 1.00 | GAA (0.55) | GAAPOLBTSHRMAPTLMNA | |
| SCHEMBL8709574 | 0.90 | ALDH1A1 (0.53) | GAAPOLBTSHRMAPTLMNA | |
| SCHEMBL21954283 | 0.85 | PTGS2 (0.64) | GAAPOLBTSHRMAPTLMNA | |
| SCHEMBL29630278 | 0.84 | GAA (0.74) | GAAPOLBTSHRMAPTLMNA | |
| SCHEMBL18516834 | 0.84 | GAA (0.57) | GAAPOLBTSHRMAPTLMNA | |
| SCHEMBL5881512 | 0.84 | GAA (0.74) | GAAPOLBTSHRMAPTLMNA | |
| SCHEMBL15019934 | 0.83 | SLC26A4 (0.64) | POLBTSHRLMNAMEN1KMT2A | |
| SCHEMBL15287154 | 0.82 | SMN1; SMN2 (0.56) | GAAPOLBTSHRMAPTLMNA | |
| SCHEMBL23218476 | 0.81 | SLC22A12 (0.53) | POLBTSHRMAPTLMNAMEN1 | |
| SCHEMBL29852438 | 0.81 | SLC22A12 (0.53) | POLBTSHRMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |