SCHEMBL29853076

SCHEMBL29853076

CCOC(=O)Cc1ccccc1OCc1cc(Br)c2oc(CCO)cc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 9/20 0.40
TBXAS1 P24557 1/20 0.40
PRMT5 O14744 1/20 0.36
PTGER1 P34995 1/20 0.36
PTGER4 P35408 1/20 0.36
PTGER3 P43115 1/20 0.36
PTGER2 P43116 1/20 0.36
TPSB2 P20231 3/20 0.35
F11 P03951 2/20 0.35
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
PLG P00747 1/20 0.35
PLAU P00749 1/20 0.35
KLKB1 P03952 1/20 0.35
F7 P08709 1/20 0.35
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
CYP4F2 P78329 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23218248 1.00 CFD (0.40) CFDTBXAS1PRMT5PTGER1PTGER4
SCHEMBL29853099 0.94 TBXAS1 (0.43) CFDTBXAS1PRMT5PTGER1PTGER4
SCHEMBL25881261 0.94 CFD (0.41) CFDTBXAS1PRMT5PTGER1PTGER4
SCHEMBL23218765 0.94 TBXAS1 (0.43) CFDTBXAS1PRMT5PTGER1PTGER4
SCHEMBL21437875 0.90 CFD (0.41) CFDTBXAS1PRMT5PTGER1PTGER4
SCHEMBL21437899 0.89 TBXAS1 (0.40) CFDTBXAS1PRMT5PTGER1PTGER4
SCHEMBL21437602 0.88 TBXAS1 (0.43) CFDTBXAS1PRMT5PTGER1PTGER4
SCHEMBL21438073 0.86 TBXAS1 (0.40) CFDTBXAS1PRMT5PTGER1PTGER4
SCHEMBL29852799 0.86 TBXAS1 (0.40) CFDTBXAS1PRMT5PTGER1PTGER4
SCHEMBL21437433 0.86 CFD (0.42) CFDTBXAS1PRMT5PTGER1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4041238-A1 ORAL COMPLEMENT FACTOR D INHIBITORS Biocryst Pharmaceuticals, Inc. (US) 2022-08-17 EP disclosed