Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 7/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218765 | 1.00 | TBXAS1 (0.43) | TBXAS1CFDPRMT5PTGER1PTGER4 | |
| SCHEMBL25881261 | 0.94 | CFD (0.41) | TBXAS1CFDPRMT5PTGER1PTGER4 | |
| SCHEMBL29853076 | 0.94 | CFD (0.40) | TBXAS1CFDPRMT5PTGER1PTGER4 | |
| SCHEMBL23218248 | 0.94 | CFD (0.40) | TBXAS1CFDPRMT5PTGER1PTGER4 | |
| SCHEMBL21438073 | 0.91 | TBXAS1 (0.40) | TBXAS1CFDPRMT5PTGER1PTGER4 | |
| SCHEMBL29852799 | 0.91 | TBXAS1 (0.40) | TBXAS1CFDPRMT5PTGER1PTGER4 | |
| SCHEMBL21437875 | 0.91 | CFD (0.41) | TBXAS1CFDPRMT5PTGER1PTGER4 | |
| SCHEMBL21437602 | 0.88 | TBXAS1 (0.43) | TBXAS1CFDPRMT5PTGER1PTGER4 | |
| SCHEMBL21439279 | 0.88 | TBXAS1 (0.39) | TBXAS1CFDPRMT5MAOBALDH1A1 | |
| SCHEMBL21438612 | 0.87 | CFD (0.42) | TBXAS1CFDPRMT5PTGER1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |