Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 4/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218258 | 1.00 | CFD (0.40) | CFDMTNR1AMTNR1BPLGPLAU | |
| SCHEMBL29592608 | 0.91 | CFD (0.47) | CFDMTNR1AMTNR1BPLGPLAU | |
| SCHEMBL23218053 | 0.91 | CFD (0.47) | CFDMTNR1AMTNR1BPLGPLAU | |
| SCHEMBL29852493 | 0.90 | CFD (0.49) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218526 | 0.90 | CFD (0.49) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218408 | 0.90 | CFD (0.42) | CFDMTNR1AMTNR1BPLGPLAU | |
| SCHEMBL29852911 | 0.90 | MTNR1A (0.43) | CFDMTNR1AMTNR1BPLGPLAU | |
| SCHEMBL23218037 | 0.90 | MTNR1A (0.43) | CFDMTNR1AMTNR1BPLGPLAU | |
| SCHEMBL29852732 | 0.90 | CFD (0.42) | CFDMTNR1AMTNR1BPLGPLAU | |
| SCHEMBL23218472 | 0.87 | MTNR1A (0.41) | CFDMTNR1AMTNR1BPLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |