Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218279 | 1.00 | CFD (0.41) | CFDDPP4ALOX5ALDH1A1HPGD | |
| SCHEMBL29852955 | 0.90 | DPP4 (0.42) | CFDDPP4ALOX5ALDH1A1HPGD | |
| SCHEMBL23218076 | 0.90 | DPP4 (0.42) | CFDDPP4ALOX5ALDH1A1HPGD | |
| SCHEMBL29592859 | 0.89 | CFD (0.46) | CFDALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL23218510 | 0.89 | CFD (0.46) | CFDALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL29340027 | 0.89 | ALDH1A1 (0.40) | CFDALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL23218624 | 0.87 | ALDH1A1 (0.38) | CFDALOX5ALDH1A1HPGDTSHR | |
| SCHEMBL29852653 | 0.87 | ALDH1A1 (0.38) | CFDALOX5ALDH1A1HPGDTSHR | |
| SCHEMBL23218363 | 0.83 | TBXAS1 (0.37) | CFDDPP4ALOX5ALDH1A1HPGD | |
| SCHEMBL29852490 | 0.83 | TBXAS1 (0.37) | CFDDPP4ALOX5ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |