Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.62 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.54 |
| ▸ | MC4R | P32245 | 2/20 | 0.54 |
| ▸ | MC5R | P33032 | 2/20 | 0.54 |
| ▸ | MC3R | P41968 | 2/20 | 0.54 |
| ▸ | MC1R | Q01726 | 2/20 | 0.54 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411096 | 0.97 | C5AR1 (0.60) | C5AR1IL23RMC4RMC5RMC3R | |
| SCHEMBL29853326 | 0.95 | C5AR1 (0.63) | C5AR1IL23RMC4RMC5RMC3R | |
| SCHEMBL31411094 | 0.93 | C5AR1 (0.63) | C5AR1IL23RMC4RMC5RMC3R | |
| SCHEMBL13144634 | 0.93 | C5AR1 (0.60) | C5AR1IL23RMC4RMC5RMC3R | |
| SCHEMBL29853485 | 0.92 | C5AR1 (0.62) | C5AR1IL23RMC4RMC5RMC3R | |
| SCHEMBL29547115 | 0.91 | C5AR1 (0.60) | C5AR1KISS1RCXCR4DPP3 | |
| SCHEMBL30518034 | 0.90 | IL23R (0.64) | C5AR1IL23RMC4RMC5RMC3R | |
| SCHEMBL13144891 | 0.88 | KISS1R (0.58) | C5AR1IL23RMC4RMC5RMC3R | |
| SCHEMBL30711762 | 0.88 | C5AR1 (0.55) | C5AR1IL23RKISS1RCXCR4DPP3 | |
| SCHEMBL17642339 | 0.88 | CTSL (0.57) | IL23RKISS1RCXCR4CXCL8DPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308114-B1 | C5AR1 INHIBITORS FOR TREATING HYPERSENSITIVITY REACTIONS TO TAXANES | DOMPE FARM SPA (IT) | 2026-02-11 | — | — | EP | claimed |
| EP-4397306-A1 | C5AR1 INHIBITORS FOR USE IN THE TREATMENT OF OCULAR MUCOUS MEMBRANE PEMPHIGOID AND/OR ORAL MUCOUS MEMBRANE PEMPHIGOID | Dompe' Farmaceutici S.P.A. (IT) | 2024-07-10 | — | — | EP | claimed |
| US-20240180888-A1 | C5AR1 INHIBITORS FOR TREATING HYPERSENSITIVITY REACTIONS TO TAXANES | DOMPE' FARMACEUTICI SPA (IT) | 2024-06-06 | — | — | US | claimed |
| EP-4059497-A1 | C5AR1 INHIBITORS FOR TREATING HYPERSENSITIVITY REACTIONS TO TAXANES | Dompé farmaceutici S.p.a. (IT) | 2022-09-21 | — | — | EP | claimed |
| EP-4308114-B1 | C5AR1 INHIBITORS FOR TREATING HYPERSENSITIVITY REACTIONS TO TAXANES | DOMPE FARM SPA (IT) | 2026-02-11 | — | — | EP | disclosed |
| EP-4397306-A1 | C5AR1 INHIBITORS FOR USE IN THE TREATMENT OF OCULAR MUCOUS MEMBRANE PEMPHIGOID AND/OR ORAL MUCOUS MEMBRANE PEMPHIGOID | Dompe' Farmaceutici S.P.A. (IT) | 2024-07-10 | — | — | EP | disclosed |
| US-20240180888-A1 | C5AR1 INHIBITORS FOR TREATING HYPERSENSITIVITY REACTIONS TO TAXANES | DOMPE' FARMACEUTICI SPA (IT) | 2024-06-06 | — | — | US | disclosed |
| US-11857600-B2 | GPCR heteromer inhibitors and uses thereof | GPCR THERAPEUTICS, INC. (KR) | 2024-01-02 | — | — | US | disclosed |
| EP-4059497-A1 | C5AR1 INHIBITORS FOR TREATING HYPERSENSITIVITY REACTIONS TO TAXANES | Dompé farmaceutici S.p.a. (IT) | 2022-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240180888-A1 | C5AR1 INHIBITORS FOR TREATING HYPERSENSITIVITY REACTIONS TO TAXANES | C5AR1, C5AR2, C3AR1 | C5AR1 1/4885IL23R 97/4885MC4R 2706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.