Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387178 | 0.83 | THRB (0.40) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL1160265 | 0.83 | THRB (0.40) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL1196063 | 0.83 | THRB (0.40) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL2963336 | 0.79 | TSHR (0.41) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL2849502 | 0.79 | SLC1A3 (0.48) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL26940426 | 0.77 | ALDH1A1 (0.38) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL8085167 | 0.77 | ALDH1A1 (0.38) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL11382908 | 0.77 | TDP1 (0.36) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7582653 | 0.77 | GPR84 (0.44) | TP53 | |
| SCHEMBL7582656 | 0.77 | GPR84 (0.44) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10551566-B2 | Method of preparing an optical connector and optical devices comprising the optical connector prepared thereby | DOW SILICONES CORPORATION (US) | 2020-02-04 | — | — | US | disclosed |
| US-10435585-B2 | Curable composition, method of preparing cured article, and cured article formed thereby | DOW CORNING CORPORATION (US) | 2019-10-08 | — | — | US | disclosed |
| EP-2996867-B1 | METHOD OF PREPARING AN ARTICLE AND ARTICLE PREPARED THEREBY | DOW SILICONES CORP (US) | 2018-09-19 | — | — | EP | disclosed |
| EP-3164449-A1 | METHODS FOR PREPARING ARTICLES AND ASSOCIATED ARTICLES PREPARED THEREBY | Dow Corning Corporation (US) | 2017-05-10 | — | — | EP | disclosed |
| US-20170107331-A1 | Methods For Preparing Articles And Associated Articles Prepared Thereby | DOW CORNING CORPORATION (US) | 2017-04-20 | — | — | US | disclosed |
| US-20160349455-A1 | METHOD OF PREPARING AN OPTICAL CONNECTOR AND OPTICAL DEVICES COMPRISING THE OPTICAL CONNECTOR PREPARED THEREBY | DOW SILICONES CORPORATION | 2016-12-01 | — | — | US | disclosed |
| US-20160102226-A1 | Curable Composition, Method Of Preparing Cured Article, And Cured Article Formed Thereby | DOW SILICONES CORPORATION | 2016-04-14 | — | — | US | disclosed |
| EP-2996867-A1 | METHOD OF PREPARING AN ARTICLE AND ARTICLE PREPARED THEREBY | Dow Corning Corporation (US) | 2016-03-23 | — | — | EP | disclosed |
| EP-2997101-A1 | CURABLE COMPOSITION, METHOD OF PREPARING CURED ARTICLE, AND CURED ARTICLE FORMED THEREBY | Dow Corning Corporation (US) | 2016-03-23 | — | — | EP | disclosed |
| US-20160077279-A1 | Method of Preparing an Article and Article Prepared Thereby | DOW SILICONES CORPORATION | 2016-03-17 | — | — | US | disclosed |
| WO-2016003636-A1 | METHODS FOR PREPARING ARTICLES AND ASSOCIATED ARTICLES PREPARED THEREBY | DOW CORNING CORPORATION (US) | 2016-01-07 | — | — | WO | disclosed |
| WO-2014186549-A1 | METHOD OF PREPARING AN ARTICLE AND ARTICLE PREPARED THEREBY | DOW CORNING CORPORATION (US) | 2014-11-20 | — | — | WO | disclosed |
| WO-2014186514-A1 | CURABLE COMPOSITION, METHOD OF PREPARING CURED ARTICLE, AND CURED ARTICLE FORMED THEREBY | DOW CORNING CORPORATION (US) | 2014-11-20 | — | — | WO | disclosed |
| EP-1692209-B1 | ACTIVE ENERGY RAY-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION, LIGHT-TRANSMITTING COMPONENT, AND METHOD FOR MANUFACTURING THE LIGHT-TRANSMITTING COMPONENT | DOW CORNING TORAY CO LTD (JP) | 2013-10-02 | — | — | EP | disclosed |
| US-7771794-B2 | Active energy ray-curable, organopolysiloxane resin composition, light-transmitting component, and method for manufacturing the light-transmitting component | DOW CORNING CORPORATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-20080058441-A1 | Active Energy Ray-Curable, Organopolysiloxane Resin Composition, Light-Transmitting Component, And Method For Manufacturing The Light-Transmitting Component | DOW TORAY CO., LTD. (JP) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10435585-B2 | Curable composition, method of preparing cured article, and cured article formed thereby | SETDB1, SETD2, SETD1A | MMP1 2637/4885MMP2 3938/4885MMP3 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.