Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
| ▸ | PTGES | O14684 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853816 | 0.89 | GAA (0.45) | HSD17B10GAAKMT2AMEN1ALOX5 | |
| SCHEMBL29853890 | 0.82 | ALOX5 (0.47) | KMT2AMEN1ALOX5PTGESSMN1; SMN2 | |
| SCHEMBL28354200 | 0.81 | LMNA (0.52) | HSD17B10GAAKMT2AMEN1POLB | |
| SCHEMBL29695464 | 0.81 | LMNA (0.52) | HSD17B10GAAKMT2AMEN1POLB | |
| SCHEMBL28354197 | 0.76 | ALOX5 (0.34) | ALOX5PTGES | |
| SCHEMBL720878 | 0.74 | ALDH1A1 (0.42) | HSD17B10GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8285723 | 0.71 | GAA (0.42) | HSD17B10GAAKMT2AMEN1ALOX5 | |
| SCHEMBL28353850 | 0.69 | AAK1 (0.33) | POLB | |
| SCHEMBL18726137 | 0.68 | GAA (0.40) | HSD17B10GAAKMT2AMEN1ALOX5 | |
| SCHEMBL28631266 | 0.68 | MAPT (0.57) | HSD17B10GAAKMT2AMEN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | claimed |
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |