SCHEMBL29854091

SCHEMBL29854091

O=C1CC(O)C(=O)N1c1cc(Cl)cc(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.53
HSD17B10 Q99714 2/20 0.53
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
MAPT P10636 2/20 0.52
GAA P10253 1/20 0.52
ALOX15 P16050 1/20 0.52
ALOX12 P18054 1/20 0.52
ADAM17 P78536 1/20 0.41
TSHR P16473 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
HSP90AA1 P07900 1/20 0.39
USP2 O75604 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
CYP2C19 P33261 1/20 0.38
GFER P55789 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10568754 0.79 ALDH1A1 (0.54) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL11405713 0.78 ALDH1A1 (0.53) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL10889600 0.78 ALDH1A1 (0.53) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL9825008 0.78 ALDH1A1 (0.53) ALDH1A1HSD17B10MEN1KMT2AMAPT
Bromide SCHEMBL11272474 0.76 ALDH1A1 (0.51) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL8530088 0.76 MT-CO2 (0.55) ALDH1A1MEN1KMT2AMAPTGAA
SCHEMBL11261682 0.74 ALDH1A1 (0.46) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL11751976 0.73 ALDH1A1 (0.76) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL11264416 0.72 ALDH1A1 (0.41) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL11044901 0.72 MT-CO2 (0.51) ALDH1A1HSD17B10MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255987-A1 USE OF ENDOGENOUS ASPARTOACYLASE PROMOTER ELEMENTS FOR TISSUE-RESTRICTED EXPRESSION OF GENE THERAPIES UNIVERSITY OF MASSACHUSETTS (US) 2025-08-14 US claimed
CN-117219796-B Pt-Pd dendrite hollow nanowire catalyst, and preparation method and application thereof 武汉理工大学 2024-02-13 CN claimed
CN-117219796-A Pt-Pd dendrite hollow nanowire catalyst, and preparation method and application thereof 武汉理工大学 2023-12-12 CN claimed
WO-2023205600-A2 USE OF ENDOGENOUS ASPARTOACYLASE PROMOTER ELEMENTS FOR TISSUE-RESTRICTED EXPRESSION OF GENE THERAPIES UNIVERSITY OF MASSACHUSETTS (US) 2023-10-26 WO claimed
EP-4632771-A1 A METHOD FOR RAPID SINTERING OF RARE-EARTH MAGNET POWDERS BASED ON THERMAL RADIATION AND/OR CONVECTION Jozef Stefan Institute (SI) 2025-10-15 EP disclosed
US-20250255987-A1 USE OF ENDOGENOUS ASPARTOACYLASE PROMOTER ELEMENTS FOR TISSUE-RESTRICTED EXPRESSION OF GENE THERAPIES UNIVERSITY OF MASSACHUSETTS (US) 2025-08-14 US disclosed
CN-117219796-B Pt-Pd dendrite hollow nanowire catalyst, and preparation method and application thereof 武汉理工大学 2024-02-13 CN disclosed
CN-117219796-B Pt-Pd dendrite hollow nanowire catalyst, and preparation method and application thereof 武汉理工大学 2024-02-13 CN disclosed
CN-117219796-A Pt-Pd dendrite hollow nanowire catalyst, and preparation method and application thereof 武汉理工大学 2023-12-12 CN disclosed
CN-117219796-A Pt-Pd dendrite hollow nanowire catalyst, and preparation method and application thereof 武汉理工大学 2023-12-12 CN disclosed
WO-2023205600-A2 USE OF ENDOGENOUS ASPARTOACYLASE PROMOTER ELEMENTS FOR TISSUE-RESTRICTED EXPRESSION OF GENE THERAPIES UNIVERSITY OF MASSACHUSETTS (US) 2023-10-26 WO disclosed
US-20220298501-A1 CRISPR-ASSOCIATED MU TRANSPOSASE SYSTEMS THE BROAD INSTITUTE, INC. (US) 2022-09-22 US disclosed