Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856204 | 0.85 | SRD5A2 (0.49) | SRD5A2ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL29856194 | 0.84 | SRD5A2 (0.47) | SRD5A2ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL29856222 | 0.84 | SRD5A2 (0.47) | SRD5A2ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL29856147 | 0.84 | LMNA (0.36) | ALDH1A1HTTSMN1; SMN2MAPTCYP19A1 | |
| SCHEMBL29856187 | 0.82 | SRD5A2 (0.47) | SRD5A2ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL29856151 | 0.80 | MAOB (0.51) | SRD5A2ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL29856328 | 0.78 | MEN1 (0.46) | SRD5A2ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL29856206 | 0.76 | SRD5A2 (0.48) | SRD5A2ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL29856299 | 0.75 | SMN1; SMN2 (0.49) | SRD5A2ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL29856242 | 0.75 | SRD5A2 (0.46) | SRD5A2ALDH1A1HTTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |