Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.61 |
| ▸ | BRAF | P15056 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | BTK | Q06187 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | BCR | P11274 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856915 | 1.00 | KIT (0.61) | KITBRAFRAB9ANPC1BTK | |
| SCHEMBL29856430 | 0.90 | BRAF (0.62) | KITBRAFRAB9ANPC1BTK | |
| SCHEMBL29562197 | 0.86 | KIT (0.77) | KITBRAFABL1EGFR | |
| SCHEMBL14318406 | 0.86 | KIT (0.77) | KITBRAFABL1EGFR | |
| SCHEMBL25245565 | 0.86 | LMNA (0.56) | KITBRAFLMNAMAPTABL1 | |
| Hydrochloric Acid SCHEMBL29833672 | 0.85 | KIT (0.75) | KITBRAFABL1EGFR | |
| SCHEMBL16755338 | 0.84 | KIT (0.78) | KITBRAFABL1 | |
| SCHEMBL29856255 | 0.84 | KIT (0.78) | KITBRAFABL1 | |
| SCHEMBL30486132 | 0.82 | LMNA (0.55) | KITBRAFLMNAMAPTABL1 | |
| SCHEMBL17664555 | 0.81 | KIT (0.74) | KITBRAFABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484482-B | Alkynyl pyrimidine or alkynyl pyridine compound, and composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-06-21 | — | — | CN | disclosed |