SCHEMBL29856332

SCHEMBL29856332

COc1cc(Cl)cc2nc3c(C)c(Br)ccc3nc12

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 11/20 0.46
AMY1A P0DUB6 6/20 0.45
POLB P06746 2/20 0.40
MAPT P10636 2/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
G6PD P11413 1/20 0.40
PKM P14618 1/20 0.40
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
CASP6 P55212 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CRHR1 P34998 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29856188 0.85 NQO2 (0.45) NQO2AMY1APOLBMAPTRAB9A
SCHEMBL29856798 0.81 NQO2 (0.54) NQO2AMY1APOLBMAPTRAB9A
SCHEMBL29856285 0.79 AMY1A (0.39) NQO2AMY1APOLBMAPTRAB9A
SCHEMBL29856490 0.78 NQO2 (0.61) NQO2AMY1APOLBMAPTRAB9A
SCHEMBL29856420 0.77 NQO2 (0.56) NQO2AMY1APOLBMAPTRAB9A
SCHEMBL29856360 0.75 NQO2 (0.66) NQO2POLBMAPTRAB9ANPC1
SCHEMBL29856352 0.75 NQO2 (0.47) NQO2POLBMAPTRAB9ANPC1
SCHEMBL29856252 0.72 NQO2 (0.50) NQO2AMY1APOLBMAPTRAB9A
SCHEMBL29856191 0.72 NQO2 (0.47) NQO2POLBMAPTRAB9ANPC1
SCHEMBL23589537 0.71 NQO2 (0.68) NQO2AMY1APOLBMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US disclosed
US-20220289689-A1 3-SUBSTITUTED PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289689-A1 3-SUBSTITUTED PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS ROS1, NOX4, NOX5 NQO2 139/4885AMY1A 4605/4885POLB 597/4885
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents ROS1, NOX4, NOX5 NQO2 139/4885AMY1A 4605/4885POLB 597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.