SCHEMBL29856285

SCHEMBL29856285

Cc1c(Br)ccc2nc3c(O)cc(Cl)cc3nc12

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 7/20 0.39
NQO2 P16083 5/20 0.37
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPK1 P28482 1/20 0.35
ACHE P22303 1/20 0.34
EPRS1 P07814 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29856307 0.84 MAPT (0.51) AMY1ANQO2MAPTKDM4EMAPK1
SCHEMBL29856332 0.79 NQO2 (0.46) AMY1ANQO2MAPTALDH1A1KMT2A
SCHEMBL29856225 0.78 NQO2 (0.50) AMY1ANQO2MAPTACHEALDH1A1
SCHEMBL29856293 0.75 NQO2 (0.50) NQO2MAPTKDM4EMAPK1ACHE
SCHEMBL29856269 0.75 NQO2 (0.50) NQO2MAPTKDM4EMAPK1ACHE
SCHEMBL29856318 0.75 NQO2 (0.42) NQO2MAPTKDM4EALDH1A1KMT2A
SCHEMBL29856223 0.72 MAPT (0.57) NQO2MAPTKDM4EACHEALDH1A1
SCHEMBL29857002 0.72 KDM4E (0.34) AMY1ANQO2MAPTKDM4EMAPK1
SCHEMBL29856316 0.71 ALDH1A1 (0.46) NQO2MAPTKDM4EMAPK1ACHE
SCHEMBL11421482 0.70 NQO2 (0.61) NQO2MAPTKDM4EMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US disclosed
US-20220289689-A1 3-SUBSTITUTED PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289689-A1 3-SUBSTITUTED PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS ROS1, NOX4, NOX5 AMY1A 4605/4885NQO2 139/4885MAPT 3143/4885
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents ROS1, NOX4, NOX5 AMY1A 4605/4885NQO2 139/4885MAPT 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.