Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 8/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856218 | 0.93 | SLC22A12 (0.44) | SLC22A12ROCK2ADORA3ADORA2A | |
| SCHEMBL29856150 | 0.89 | SLC22A12 (0.42) | SLC22A12ROCK2ADORA3ADORA2A | |
| SCHEMBL29856198 | 0.85 | ELANE (0.41) | SLC22A12ROCK2ADORA3ADORA2AMELK | |
| SCHEMBL29856251 | 0.85 | ELANE (0.41) | SLC22A12ROCK2ADORA3ADORA2AMELK | |
| SCHEMBL29856309 | 0.82 | SLC22A12 (0.39) | SLC22A12ROCK2ADORA3ADORA2ACYP3A4 | |
| SCHEMBL29856235 | 0.82 | SLC22A12 (0.39) | SLC22A12ROCK2ADORA3ADORA2ARORC | |
| SCHEMBL29856274 | 0.80 | ROCK2 (0.36) | ROCK2ADORA3ADORA2A | |
| SCHEMBL29856329 | 0.76 | ELANE (0.41) | SLC22A12ROCK2ADORA3ADORA2A | |
| SCHEMBL29856387 | 0.73 | SLC22A12 (0.46) | SLC22A12ROCK2ADORA3ADORA2A | |
| SCHEMBL29856402 | 0.73 | SLC22A12 (0.31) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |