Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856218 | 0.79 | SLC22A12 (0.44) | SLC22A12 | |
| SCHEMBL29856150 | 0.75 | SLC22A12 (0.42) | SLC22A12 | |
| SCHEMBL29856491 | 0.73 | SLC22A12 (0.38) | SLC22A12 | |
| SCHEMBL29856265 | 0.72 | SLC22A12 (0.47) | SLC22A12 | |
| SCHEMBL29856251 | 0.71 | ELANE (0.41) | SLC22A12 | |
| SCHEMBL29856309 | 0.66 | SLC22A12 (0.39) | SLC22A12TTR | |
| SCHEMBL29856274 | 0.62 | ROCK2 (0.36) | — | |
| SCHEMBL3422274 | 0.59 | TTR (0.68) | SLC22A12TTR | |
| SCHEMBL29856387 | 0.58 | SLC22A12 (0.46) | SLC22A12 | |
| SCHEMBL11338682 | 0.58 | TTR (0.60) | TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |