Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 4/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30019255 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL184685 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL2537894 | 0.91 | CYP1A2 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL2537974 | 0.91 | CYP1A2 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL262425 | 0.91 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL30951774 | 0.91 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL30092831 | 0.91 | CYP1A2 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL29373271 | 0.91 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL29733623 | 0.91 | CYP1A2 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL5887748 | 0.91 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114767704-B | Medicine structure capable of targeting hepatitis B virus and medicine composition | 圣诺制药公司 | 2024-06-14 | — | — | CN | disclosed |
| US-20230392154-A1 | TARGETED NUCLEIC ACID THERAPY FOR HEPATITIS B | SIRNAOMICS, INC. | 2023-12-07 | — | — | US | disclosed |
| WO-2022172083-A2 | TARGETED NUCLEIC ACID THERAPY FOR HEPATITIS B | SIRNAOMICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230392154-A1 | TARGETED NUCLEIC ACID THERAPY FOR HEPATITIS B | HAVCR2, POLRMT, FABP1 | ALDH1A1 2500/4885HSD17B10 1357/4885CYP1A2 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.