Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.46 |
| ▸ | GRB2 | P62993 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29858341 | 0.93 | CASP3 (0.45) | CASP3GRB2PTPN1MDM4TP53 | |
| SCHEMBL29693009 | 0.86 | CASP3 (0.59) | CASP3MDM4TP53MDM2 | |
| SCHEMBL29505149 | 0.84 | CASP3 (0.56) | CASP3PTPN1MDM4TP53 | |
| SCHEMBL30163429 | 0.83 | PTPN1 (0.56) | CASP3GRB2PTPN1CTSBCTSK | |
| SCHEMBL31355420 | 0.81 | CASP3 (0.49) | CASP3CTSBMDM4TP53 | |
| SCHEMBL29051485 | 0.81 | CASP3 (0.49) | CASP3CTSBMDM4TP53 | |
| SCHEMBL30892068 | 0.81 | PTPN1 (0.49) | CASP3PTPN1CTSBCTSKMDM4 | |
| SCHEMBL30945914 | 0.81 | MDM4 (0.48) | CASP3GRB2PTPN1MDM4TP53 | |
| SCHEMBL15866464 | 0.80 | PTPN1 (0.53) | CASP3PTPN1CTSKMDM4TP53 | |
| SCHEMBL30945915 | 0.79 | CTSB (0.51) | CASP3PTPN1CTSBCTSKMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160429-A | Preparation method of Tirzepatide | 深圳市健元医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |