Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 8/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30056577 | 0.89 | NAALAD2 (0.50) | NAALAD2BACE1KEAP1BACE2OPRM1 | |
| SCHEMBL31347347 | 0.86 | GLP1R (0.51) | OPRM1OPRD1GLP1R | |
| SCHEMBL30054207 | 0.85 | BACE1 (0.51) | NAALAD2BACE1BACE2OPRM1OPRD1 | |
| SCHEMBL29858785 | 0.85 | OPRD1 (0.53) | OPRM1OPRD1 | |
| SCHEMBL30721545 | 0.84 | GLP1R (0.58) | KEAP1OPRM1OPRD1GLP1R | |
| SCHEMBL29858485 | 0.84 | KEAP1 (0.38) | NAALAD2KEAP1 | |
| SCHEMBL10082823 | 0.82 | KEAP1 (0.44) | BACE1KEAP1OPRM1OPRD1SYK | |
| SCHEMBL31003041 | 0.81 | OPRD1 (0.63) | BACE1BACE2OPRM1OPRD1 | |
| SCHEMBL29602768 | 0.81 | OPRM1 (0.62) | BACE1KEAP1BACE2OPRM1OPRD1 | |
| SCHEMBL29984972 | 0.80 | OPRM1 (0.43) | BACE1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160429-A | Preparation method of Tirzepatide | 深圳市健元医药科技有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-115160429-A | Preparation method of Tirzepatide | 深圳市健元医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |