Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28726425 | 0.89 | TSHR (0.53) | ALDH1A1HSD17B10CFTRGAAMAPT | |
| SCHEMBL23645723 | 0.84 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CFTRGAAMAPT | |
| SCHEMBL5034729 | 0.84 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CFTRGAAMAPT | |
| SCHEMBL11289979 | 0.84 | EGFR (0.50) | ALDH1A1HSD17B10CFTRGAAMAPT | |
| SCHEMBL29141387 | 0.83 | LMNA (0.47) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL6833625 | 0.82 | IKBKB (0.49) | ALDH1A1HSD17B10GAAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL27544982 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CFTRGAAMAPT | |
| SCHEMBL28901175 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CFTRGAAMAPT | |
| SCHEMBL421466 | 0.81 | IKBKB (0.65) | ALDH1A1HSD17B10CFTRGAAMAPT | |
| SCHEMBL1317476 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CFTRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398097-B2 | WDR5-MYC inhibitors | VANDERBILT UNIVERSITY (US) | 2025-08-26 | — | — | US | disclosed |
| US-20220289673-A1 | WDR5-MYC INHIBITORS | VANDERBILT UNIVERSITY | 2022-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220289673-A1 | WDR5-MYC INHIBITORS | MYC, WDR5, MYCBP | ALDH1A1 3953/4885HSD17B10 3579/4885CFTR 3201/4885 |
| US-12398097-B2 | WDR5-MYC inhibitors | MYC, WDR5, MYCBP | ALDH1A1 3953/4885HSD17B10 3579/4885CFTR 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.