SCHEMBL29860152

SCHEMBL29860152

CCOC(=O)N(C)c1ccccc1-c1nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.40
LMNA P02545 4/20 0.40
PKM P14618 1/20 0.40
TSPO P30536 3/20 0.37
ALDH1A1 P00352 5/20 0.35
TSHR P16473 2/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
RAB9A P51151 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
GRM6 O15303 1/20 0.33
GPBAR1 Q8TDU6 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TACR1 P25103 1/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3194093 0.82 TDP1 (0.38) KDM4ELMNAPKMALDH1A1TSHR
SCHEMBL29860185 0.82 TDP1 (0.38) KDM4ELMNAPKMALDH1A1TSHR
SCHEMBL4122240 0.78 LMNA (0.38) KDM4ELMNAPKMTSPOALDH1A1
SCHEMBL4113805 0.77 LMNA (0.41) KDM4ELMNAPKMTSHRSMN1; SMN2
SCHEMBL4404209 0.75 LMNA (0.35) KDM4ELMNAPKMALDH1A1SMN1; SMN2
Urethane SCHEMBL4535413 0.73 KDM4E (0.40) KDM4ELMNAPKMALDH1A1SMN1; SMN2
SCHEMBL388905 0.72 HTT (0.44) LMNATSPOALDH1A1TSHRSMN1; SMN2
SCHEMBL946488 0.72 F2R (0.38) KDM4ELMNAPKMALDH1A1SMN1; SMN2
SCHEMBL5145779 0.72 HTT (0.44) KDM4ELMNAALDH1A1TSHRSMN1; SMN2
SCHEMBL388673 0.72 PPID (0.40) LMNAALDH1A1SMN1; SMN2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022209858-A1 UV RADIATION SENSING MEMBER AND UV RADIATION SENSING KIT 富士フイルム株式会社 2022-10-06 WO disclosed