SCHEMBL29860185

SCHEMBL29860185

CCOC(=O)CN(CC(=O)OCC)c1ccccc1-c1nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 3/20 0.36
LMNA P02545 2/20 0.36
PKM P14618 1/20 0.36
ALDH1A1 P00352 4/20 0.36
PRNP P04156 1/20 0.36
PPARG P37231 1/20 0.35
TSHR P16473 1/20 0.34
MAPK8 P45983 1/20 0.34
MAPK9 P45984 1/20 0.34
MAPK10 P53779 1/20 0.34
PIN1 Q13526 1/20 0.34
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
PTPN1 P18031 1/20 0.33
GSTO1 P78417 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3194093 1.00 TDP1 (0.38) TDP1KDM4ELMNAPKMALDH1A1
SCHEMBL4404209 0.91 LMNA (0.35) TDP1KDM4ELMNAPKMALDH1A1
SCHEMBL29860175 0.83 KDM4E (0.34) KDM4ELMNAPKMALDH1A1PPARG
SCHEMBL29860152 0.82 KDM4E (0.40) KDM4ELMNAPKMALDH1A1TSHR
SCHEMBL388672 0.79 AR (0.37) KDM4ELMNAPKMALDH1A1PPARG
SCHEMBL391447 0.79 AR (0.37) KDM4ELMNAPKMALDH1A1PPARG
SCHEMBL29859903 0.78 AR (0.37) KDM4ELMNAPKMALDH1A1PPARG
SCHEMBL394048 0.78 RAB9A (0.38) KDM4ELMNAPKMALDH1A1PPARG
SCHEMBL388904 0.78 AR (0.37) KDM4ELMNAPKMALDH1A1PPARG
SCHEMBL320984 0.78 RAB9A (0.39) TDP1KDM4ELMNAPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022209858-A1 UV RADIATION SENSING MEMBER AND UV RADIATION SENSING KIT 富士フイルム株式会社 2022-10-06 WO disclosed