Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | SNCA | P37840 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11772851 | 0.82 | CTDSP1 (0.47) | ALDH1A1MEN1KMT2AMCL1DNMT1 | |
| SCHEMBL29363189 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMCL1DNMT1 | |
| SCHEMBL29374267 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMCL1CDK2 | |
| SCHEMBL1187339 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMCL1CDK2 | |
| SCHEMBL70219 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMCL1DNMT1 | |
| SCHEMBL6544874 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMCL1DNMT1 | |
| SCHEMBL5356612 | 0.79 | CDK2 (0.47) | ALDH1A1MEN1KMT2AMCL1DNMT1 | |
| SCHEMBL28357450 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMCL1CDK2 | |
| SCHEMBL29405571 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMCL1CDK2 | |
| SCHEMBL7126508 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMCL1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630566-B2 | KRas G12D inhibitors | Mirati Therapeutics, Inc. (US) | 2026-05-19 | — | — | US | disclosed |
| US-20240309020-A1 | KRAS G12D INHIBITORS | ARRAY BIOPHARMA INC. | 2024-09-19 | — | — | US | disclosed |
| US-11964989-B2 | KRas G12D inhibitors | Mirati Therapeutics, Inc. (US) | 2024-04-23 | — | — | US | disclosed |
| CN-114615981-B | KRAS G12D inhibitors | 米拉蒂治疗股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117865902-A | Organic electronic transmission material, light emitting device and display panel | 京东方科技集团股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117660992-A | Synthesis method of organosilicon compound containing Si-O bond | 新疆大学 | 2024-03-08 | — | — | CN | disclosed |
| US-20230389423-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-11-30 | — | — | US | disclosed |
| US-20230389423-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-11-30 | — | — | US | disclosed |
| CN-114230702-B | Olefin polymerization catalyst with naphthoxy skeleton, preparation method and application | 万华化学集团股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230279025-A1 | KRAS G12D INHIBITORS | ARRAY BIOPHARMA INC. | 2023-09-07 | — | — | US | disclosed |
| WO-1998017616-A1 | PRODUCTION OF NABUMETONE OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1998-04-30 | — | — | WO | disclosed |
| EP-0416038-B1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX INC (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0416038-A4 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | — | 1992-02-26 | — | — | EP | disclosed |
| EP-0416038-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED. | TROPIX INC (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4952707-A | DECOMPOSITION TO LIGHT EMITTING FLUOROPHORE; ANALYSIS | TROPIX, INC. (US) | 1990-08-28 | — | — | US | disclosed |
| WO-1990000164-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX, INC. (US) | 1990-01-11 | — | — | WO | disclosed |
| US-4061642-A | AZO DYE INTERMEDIATES | CASSELLA FARBWERKE MAINKUR AG (DT) | 1977-12-06 | — | — | US | disclosed |
| US-3956294-A | AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
| US-3954782-A | 2,6-Hydrazino-3-pyridine carboxyamides | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |
| US-3947463-A | Certain 2-amino-nicotinonitrile derivatives | CASSELLA FARBWERKE MAINKUR AG (DT) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279025-A1 | KRAS G12D INHIBITORS | KRAS, NRAS, HRAS | ALDH1A1 2943/4885MEN1 456/4885KMT2A 1839/4885 |
| US-12630566-B2 | KRas G12D inhibitors | KRAS, NRAS, HRAS | ALDH1A1 1816/4885MEN1 924/4885KMT2A 2950/4885 |
| US-20230389423-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, VDAC2, KCNC1 | ALDH1A1 525/4885MEN1 1667/4885KMT2A 2184/4885 |
| US-11964989-B2 | KRas G12D inhibitors | KRAS, NRAS, HRAS | ALDH1A1 1957/4885MEN1 258/4885KMT2A 2336/4885 |
| US-20240309020-A1 | KRAS G12D INHIBITORS | KRAS, NRAS, HRAS | ALDH1A1 2681/4885MEN1 465/4885KMT2A 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.