SCHEMBL29861950

SCHEMBL29861950

CC(C)(C)c1ccc(-c2c3ccccc3c(-c3ccc(C(C)(C)C)cc3)c3cc4ccccc4cc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.47
ESR1 P03372 4/20 0.43
ESR2 Q92731 2/20 0.43
TNKS O95271 1/20 0.42
TNKS2 Q9H2K2 1/20 0.42
CCR4 P51679 1/20 0.40
KIF11 P52732 4/20 0.40
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
TNF P01375 1/20 0.39
NOD1 Q9Y239 1/20 0.39
NR1I2 O75469 1/20 0.39
LMNA P02545 1/20 0.39
ADRA2A P08913 1/20 0.39
CYP2D6 P10635 1/20 0.39
ACHE P22303 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2A P28223 1/20 0.39
SLC6A4 P31645 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1098425 1.00 GPR84 (0.47) GPR84ESR1ESR2TNKSTNKS2
SCHEMBL26214017 0.89 GPR84 (0.45) GPR84ESR1ESR2TNKSTNKS2
SCHEMBL5955995 0.88 KIF11 (0.46) GPR84TNKSTNKS2KIF11TP53
SCHEMBL2700109 0.87 GPR84 (0.55) GPR84TNKSTNKS2CCR4KIF11
SCHEMBL22978415 0.84 TNKS (0.46) GPR84TNKSTNKS2KIF11TP53
SCHEMBL30662421 0.84 TNKS (0.46) GPR84TNKSTNKS2KIF11TP53
SCHEMBL26216394 0.84 ESR1 (0.42) GPR84ESR1ESR2TNKSTNKS2
SCHEMBL14726990 0.84 HSD11B1 (0.40) GPR84TNKSTNKS2KIF11TP53
SCHEMBL26216554 0.83 GPR84 (0.52) GPR84TNKSTNKS2CCR4KIF11
SCHEMBL29350412 0.83 KIF11 (0.42) GPR84ESR1ESR2TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4069807-A1 METHOD FOR DETERMINING AUTHENTICITY AND ADULTERATION OF MARKED PETROLEUM HYDROCARBONS Sicpa Holding SA (CH) 2022-10-12 EP disclosed
EP-4069806-A1 METHOD OF MARKING A PETROLEUM HYDROCARBON Sicpa Holding SA (CH) 2022-10-12 EP disclosed