SCHEMBL29862828

SCHEMBL29862828

Cc1cc(N[C@H]2CCN(C(=O)OC(C)(C)C)C2)cc2cccnc12

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 7/20 0.48
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
GPR119 Q8TDV5 2/20 0.46
PIM1 P11309 2/20 0.45
PIM2 Q9P1W9 2/20 0.45
BTK Q06187 1/20 0.45
PARP1 P09874 1/20 0.44
BRD4 O60885 1/20 0.44
MET P08581 1/20 0.44
PIK3CD O00329 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29933640 1.00 USP30 (0.48) USP30ALDH1A1NPC1MAPTMAPK1
SCHEMBL28834162 1.00 USP30 (0.48) USP30ALDH1A1NPC1MAPTMAPK1
SCHEMBL28834163 1.00 USP30 (0.48) USP30ALDH1A1NPC1MAPTMAPK1
SCHEMBL23360437 0.94 ALDH1A1 (0.53) ALDH1A1NPC1MAPTMAPK1HTT
SCHEMBL28834087 0.90 USP30 (0.49) USP30ALDH1A1NPC1MAPTMAPK1
SCHEMBL28834057 0.90 USP30 (0.48) USP30ALDH1A1NPC1MAPTMAPK1
SCHEMBL29863292 0.90 USP30 (0.48) USP30ALDH1A1NPC1MAPTMAPK1
SCHEMBL28834089 0.90 USP30 (0.49) USP30ALDH1A1NPC1MAPTMAPK1
SCHEMBL28833988 0.90 USP30 (0.48) USP30ALDH1A1NPC1MAPTMAPK1
SCHEMBL28834138 0.90 USP30 (0.49) USP30ALDH1A1NPC1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP disclosed
CN-114867719-B Pyrrolidine and piperidine compounds 柳韩洋行 2024-06-25 CN disclosed
US-11655235-B2 Pyrrolidine and piperidine compounds YUHAN CORPORATION (KR) 2023-05-23 US disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed
CN-114867719-A Pyrrolidine and piperidine compounds 柳韩洋行 2022-08-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655235-B2 Pyrrolidine and piperidine compounds FAP, APC, VHL USP30 1231/4885ALDH1A1 439/4885NPC1 2057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.