SCHEMBL29863671

SCHEMBL29863671

CS(=O)(=O)c1ccc(OCC=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.47
CA1 P00915 6/20 0.47
CA2 P00918 6/20 0.47
CA9 Q16790 6/20 0.47
CA7 P43166 4/20 0.47
ENPP2 Q13822 1/20 0.42
TSHR P16473 1/20 0.41
PTGS2 P35354 5/20 0.40
PTGS1 P23219 2/20 0.40
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA4 P22748 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2726596 0.81 CA12 (0.42) CA12CA1CA2CA9CA7
SCHEMBL5207689 0.79 CA12 (0.63) CA12CA1CA2CA9CA7
SCHEMBL13363484 0.79 CA12 (0.47) CA12CA1CA2CA9CA7
SCHEMBL6746191 0.78 CA12 (0.68) CA12CA1CA2CA9CA7
SCHEMBL13363404 0.78 CA12 (0.47) CA12CA1CA2CA9CA7
SCHEMBL230017 0.75 DRD2 (0.48) TSHR
SCHEMBL20442679 0.75 NQO1 (0.64) CA12CA1CA2CA9CA7
SCHEMBL1951879 0.75 ALDH1A1 (0.52) CA12CA1CA2CA9CA7
SCHEMBL16519364 0.74 MMP2 (0.39) CA12CA1CA2CA9CA7
SCHEMBL13481191 0.74 CA12 (0.70) CA12CA1CA2CA9CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110143932-B Piperazinone derivatives, process for producing the same, inhibitor, and method for controlling root-parasitic weeds 南开大学 2022-09-16 CN disclosed