Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21459374 | 0.97 | HTR6 (0.32) | HTR6MDM2TP53 | |
| SCHEMBL21459657 | 0.92 | POLQ (0.33) | POLQHTR6 | |
| SCHEMBL23250487 | 0.91 | THRA (0.31) | — | |
| SCHEMBL29863760 | 0.90 | POLQ (0.32) | POLQ | |
| SCHEMBL29863621 | 0.89 | POLQ (0.32) | POLQHTR6 | |
| SCHEMBL23248902 | 0.88 | HTR6 (0.32) | HTR6 | |
| SCHEMBL29864060 | 0.88 | EPHX2 (0.32) | POLQMDM2TP53 | |
| SCHEMBL29864191 | 0.88 | HTR6 (0.33) | HTR6MDM2TP53 | |
| SCHEMBL23249152 | 0.87 | RET (0.32) | — | |
| SCHEMBL23249150 | 0.87 | EPHX2 (0.33) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045039-A1 | INHIBITING HUMAN INTEGRIN ALPHA4BETA7 | Morphic Therapeutic, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |