Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 3/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249152 | 0.97 | RET (0.32) | RETKDRSLC5A1SLC5A2SLC6A2 | |
| SCHEMBL23249219 | 0.92 | POLQ (0.34) | POLQSLC6A2SLC6A4 | |
| SCHEMBL29863674 | 0.90 | POLQ (0.31) | POLQ | |
| SCHEMBL31629452 | 0.87 | F11 (0.33) | RETKDR | |
| SCHEMBL21459374 | 0.87 | HTR6 (0.32) | SLC5A1SLC5A2MAPT | |
| SCHEMBL23250487 | 0.85 | THRA (0.31) | MAPT | |
| SCHEMBL23256558 | 0.82 | PSEN1 (0.35) | — | |
| SCHEMBL23249019 | 0.82 | SLC5A1 (0.32) | SLC5A1SLC5A2MAPT | |
| SCHEMBL29863481 | 0.82 | OPRK1 (0.32) | — | |
| SCHEMBL29863454 | 0.81 | PTGS2 (0.37) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045039-A1 | INHIBITING HUMAN INTEGRIN ALPHA4BETA7 | Morphic Therapeutic, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |