Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.58 |
| ▸ | TOP1 | P11387 | 3/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17006271 | 1.00 | STAT3 (0.58) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL10775549 | 0.81 | STAT3 (0.81) | STAT3MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL28858947 | 0.80 | IDO1 (0.52) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL2858946 | 0.80 | ALDH1A1 (0.57) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL2747236 | 0.80 | ALDH1A1 (0.52) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL10778903 | 0.79 | STAT3 (0.72) | STAT3ALDH1A1MAPTHPGDALOX15 | |
| Hydrochloric Acid SCHEMBL2747237 | 0.78 | ALDH1A1 (0.55) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL9573746 | 0.77 | STAT3 (0.46) | STAT3TOP1IDO1CDC25BPIN1 | |
| Nitrogen SCHEMBL27717856 | 0.77 | ALDH1A1 (0.53) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL8895156 | 0.77 | CDC25B (0.57) | TOP1IDO1CDC25BPIN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174526-A1 | COMPOUNDS AND MEDICAL USE THEREOF FOR COLORECTAL CANCER | 中国药科大学 | 2022-08-25 | — | — | WO | disclosed |