Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.58 |
| ▸ | TOP1 | P11387 | 3/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865019 | 1.00 | STAT3 (0.58) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL10775549 | 0.81 | STAT3 (0.81) | STAT3MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL28858947 | 0.80 | IDO1 (0.52) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL2858946 | 0.80 | ALDH1A1 (0.57) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL2747236 | 0.80 | ALDH1A1 (0.52) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL10778903 | 0.79 | STAT3 (0.72) | STAT3ALDH1A1MAPTHPGDALOX15 | |
| Hydrochloric Acid SCHEMBL2747237 | 0.78 | ALDH1A1 (0.55) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL9573746 | 0.77 | STAT3 (0.46) | STAT3TOP1IDO1CDC25BPIN1 | |
| Nitrogen SCHEMBL27717856 | 0.77 | ALDH1A1 (0.53) | STAT3TOP1IDO1CDC25BPIN1 | |
| SCHEMBL8895156 | 0.77 | CDC25B (0.57) | TOP1IDO1CDC25BPIN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12594265-B2 | Methods and compositions for inhibition of STAT3 | OHIO STATE INNOVATION FOUNDATION (US) | 2026-04-07 | — | — | US | disclosed |
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-20230103257-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF STAT3 | OHIO STATE INNOVATION FOUNDATION | 2023-03-30 | — | — | US | disclosed |
| US-11420946-B2 | Methods and compositions for inhibition of STAT3 | OHIO STATE INNOVATION FOUNDATION (US) | 2022-08-23 | — | — | US | disclosed |
| US-20200339525-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF STAT3 | OHIO STATE INNOVATION FOUNDATION | 2020-10-29 | — | — | US | disclosed |
| US-20200339525-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF STAT3 | OHIO STATE INNOVATION FOUNDATION | 2020-10-29 | — | — | US | disclosed |
| WO-2020206424-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-10-08 | — | — | WO | disclosed |
| EP-3687514-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF STAT3 | Ohio State Innovation Foundation (US) | 2020-08-05 | — | — | EP | disclosed |
| US-20200088732-A1 | METHODS FOR THE DIAGNOSIS AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA | UNIVERSITÉ D'AIX MARSEILLE (FR) | 2020-03-19 | — | — | US | disclosed |
| CN-104035283-B | Colored composition, ink for inkjet, color filter and its manufacture method and solid-state image sensors and display device | 富士胶片株式会社 | 2017-11-21 | — | — | CN | disclosed |
| US-9783513-B2 | STAT3 inhibitors and their anticancer use | OHIO STATE INNOVATION FOUNDATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-9783513-B2 | STAT3 inhibitors and their anticancer use | OHIO STATE INNOVATION FOUNDATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-9783513-B2 | STAT3 inhibitors and their anticancer use | OHIO STATE INNOVATION FOUNDATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-20150232434-A1 | STAT3 INHIBITORS AND THEIR ANTICANCER USE | OHIO STATE INNOVATION FOUNDATION | 2015-08-20 | — | — | US | disclosed |
| US-20150232434-A1 | STAT3 INHIBITORS AND THEIR ANTICANCER USE | OHIO STATE INNOVATION FOUNDATION | 2015-08-20 | — | — | US | disclosed |
| US-20150232434-A1 | STAT3 INHIBITORS AND THEIR ANTICANCER USE | OHIO STATE INNOVATION FOUNDATION | 2015-08-20 | — | — | US | disclosed |
| CN-102803399-B | Coloring composition, ink for ink jet, color filter and method for producing the same, solid-state image sensor and display device | FUJIFILM CORP | 2015-03-25 | — | — | CN | disclosed |
| CN-104035283-A | Colored Composition, Inkjet Ink, Color Filter And Method Of Producing The Same, Solid-state Image Sensor And Display Device | FUJIFILM CORP | 2014-09-10 | — | — | CN | disclosed |
| CN-102803399-A | Coloring composition, ink for ink jet, color filter and method for producing the same, solid-state image sensor and display device | FUJIFILM CORP | 2012-11-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200088732-A1 | METHODS FOR THE DIAGNOSIS AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA | STAT3, JAK3, PLAAT3 | STAT3 1/4885TOP1 4715/4885IDO1 1857/4885 |
| US-12594265-B2 | Methods and compositions for inhibition of STAT3 | STAT3, JAK2, MALT1 | STAT3 1/4885TOP1 2818/4885IDO1 1169/4885 |
| US-20150232434-A1 | STAT3 INHIBITORS AND THEIR ANTICANCER USE | STAT3, STAT1, JAK1 | STAT3 1/4885TOP1 1480/4885IDO1 290/4885 |
| US-20230103257-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF STAT3 | STAT3, STAT1, JAK2 | STAT3 1/4885TOP1 2802/4885IDO1 457/4885 |
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | STAT3 3/4885TOP1 3024/4885IDO1 41/4885 |
| US-20200339525-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF STAT3 | STAT3, STAT1, JAK2 | STAT3 1/4885TOP1 2802/4885IDO1 457/4885 |
| US-11420946-B2 | Methods and compositions for inhibition of STAT3 | STAT3, STAT1, JAK2 | STAT3 1/4885TOP1 2802/4885IDO1 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.